Abstract：Objective To explore the clinical effect of Zhengqing Fengtongning combined with low-dose Prednisone Tablets in the treatment of idiopathic membranous nephropathy (IMN).Methods A total of 70 patients with IMN in Jiujiang Traditional Chinese Medicine Hospital from October 2018 to January 2020 were selected and divided into two groups according to the random number table method,with 35 patients in each group.The control group was treated with Prednisone Tablets,and the treatment group was treated with Zhengqing Fengtongning Sustained-release Tablets based on the control group.Treatment lasted nine months in both group.The clinical efficacy,traditional Chinese medicine symptom score and laboratory indexes between the two groups were compared.Results The total effective rate of the treatment group was higher than that of the control group,the difference was statistically significant (P＜0.05).After 3 and 9 months of treatment,the traditional Chinese medicine symptom scores of the treatment group were lower than those of the control group,and the differences were statistically significant (P＜0.05).After 3 and 9 months of treatment,the levels of albumin and fibrinogen in the treatment group were higher than those in the control group,the quantitative levels of 24 h urine protein and triacylglycerol were lower than those in the control group,and the differences were statistically significant (P＜0.05).Conclusion The clinical effect of Zhengqing Fengtongning combined with Prednisone Tablets in the treatment of IMN is remarkable.It can reduce the traditional Chinese medicine symptom score,increase the level of albumin and fibrinogen,and reduce the quantitative level of 24 h urinary protein and triacylglycerol.
Zeng CH，Chen HM，Wang RS，et al.Etiology and Clinical Characteristics of Membranous Nephropathy in Chinese Patients[J].Am J Kidney Dis，2008，52（4）：691-698.
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