Effect of antibiotic supervision and management in ICU
LI Qiu-ju1 ZHU Ya-rong2 PENG Guo-liang3
1. Department of Pharmacy and Equipment, People′s Hospital of Yingde, Guangdong Province, Yingde 513000, China;
2.Department of Critical Care Medicine,People′s Hospital of Yingde,Guangdong Province,Yingde 513000,China;
3.Department of Infection Control Branch Management, People′s Hospital of Yingde, Guangdong Province, Yingde 513000,China
Abstract：Objective To explore the application effect of antibiotics supervision and management in ICU.Methods A total of 150 patients admitted to ICU, People′s Hospital of Yingde, Guangdong Province from January 2014 to January 2015 were selected retrospectively as the control group, and 150 patients admitted from February 2015 to February 2016 were selected as the intervention group. Routine management of the use of antibiotics was carried out in the control group, and supervision and management of antibiotics was carried out in the intervention group. The utilization rate, use intensity, microbial specimen submission rate and occurrence of drug-resistant bacteria infection were compared between the two groups. Results The utilization rate of antibiotics in the intervention group was lower than that in the control group, and the difference was statistically significant (P<0.05). The intensity of antibiotics use in the intervention group was (159.84±18.04) DDDs/(100 person·days), lower than that in the control group (215.37±22.86) DDDs/(100 person·days), and the difference was statistically significant (P<0.05). The rate of microbiological specimen submission was 72.13% in ICU of the intervention group, which was higher than 46.94% in the control group, and the difference was statistically significant(P<0.05).The incidence of drug-resistant bacteria infection in the intervention group was 2.67%,lower than 8.00% in the control group, and the difference was statistically significant (P<0.05). Conclusion The monitoring and management of antibiotics in ICU ward can reduce the frequency and intensity of antibiotics use, effectively improve the rate of microbial specimen submission, and reduce the occurrence of multi-drug resistant bacteria infection.
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