化腐生肌膏联合微氧治疗Ⅳ期压疮的临床效果

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摘要目的分析化腐生肌膏联合微氧治疗Ⅳ期压疮的临床效果。方法选取2019年4月—2020年6月兴化市中医院皮肤科门诊收治的40 例Ⅳ期压疮患者作为研究对象，采用随机数字表法将其分为试验组（20 例）和对照组（20 例）。试验组患者使用化腐生肌膏联合微氧治疗，对照组患者使用灭菌凡士林，两组患者都采用清创和系统护理。比较两组患者治疗2、4 周后的创面面积减小总有效率、创面组织类型改变总有效率、创面渗液量减少总有效率；比较两组治疗前及治疗2、4 周后的长度、宽度、深度、面积、体积；比较两组治疗4 周后的创面修复总有效率。结果试验组患者治疗2 周和4 周后的创面面积减小总有效率、创面组织类型改变总有效率、创面渗液量减少总有效率均高于对照组，创面长度、宽度、深度、面积、体积值均小于对照组，差异有统计学意义（P＜0.05）。试验组治疗4 周后的创面面积减小总有效率、创面组织类型改变总有效率、创面渗液量减少总有效率均高于治疗2 周后，创面长度、宽度、深度、面积、体积值均小于治疗2 周后，差异有统计学意义（P＜0.05）。对照组治疗4 周后的创面面积减小总有效率、创面组织类型改变总有效率、创面渗液量减少总有效率高于治疗2 周后，差异有统计学意义（P＜0.05）。对照组治疗4 周后的创面长度、宽度、深度、面积、体积与治疗2 周后比较，差异无统计学意义（P＞0.05）。试验组患者治疗4 周后的创面恢复总有效率高于对照组，差异有统计学意义（P＜0.05）。结论化腐生肌膏联合微氧治疗Ⅳ期压疮的效果好，患者恢复佳，副作用小，明显提高患者的生活质量，值得临床推广。

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关键词 ： Ⅳ期压疮, 化腐生肌膏, 微氧, 护理

Abstract：Objective To analyze the clinical therapeutic effect of Huafu Shengji Paste combined with micro-aerobic therapy in the treatment of patients with stage Ⅳpressure ulcers. Methods Forty patients with stage Ⅳpressure ulcers who received the treatment in Dermatology Department of Xinghua Traditional Chinese Medicine Hospital from April 2019 to June 2020 were selected as the research subjects. The patients were divided into experimental group (20 cases)and control group (20 cases) by random number table method. The patients in the experimental group were treated with Huafu Shengji Paste combined with micro-aerobic therapy, and the patients in the control group were treated with sterile petrolatum. Both groups received debridement and systemic care. The overall response rates of wound area reduction, wound tissue type change, and wound exudate reduction were compared between the two groups after 2 and 4 weeks of treatment; the length, width, depth, area, and volume of the wound before treatment and after 2, 4 weeks of treatment of the two groups were compared; the overall response rate of wound repair were compared between the two groups after 4 weeks of treatment. Results The overall response rates of wound area reduction, wound tissue type change, wound exudate volume reduction in the experimental group were higher than those of the control group after 2 and 4 weeks of treatment, the length, width, depth, area, and volume of wound in the experimental group were all lower than those of the control group after 2 and 4 weeks of treatment, with statistically significant differences (P＜0.05). In the experimental group, the overall response rates of wound area reduction, wound tissue type change, wound exudate volume reduction after 4 weeks of treatment were higher than those after 2 weeks of treatment, the length, width, depth,area, and volume of wound after 4 weeks of treatment were lower than those after 2 weeks of treatment, and the differences were statistically significant (P＜0.05). In the control group the overall response rates of wound area reduction,wound tissue type change, wound exudate volume reduction, after 4 weeks of treatment were ligher than those after 2 weeks of treatment, the differencces were statistically significant (P＜0.05). In the control group, there were no statistical differences in the length, width, depth, area, and volume of wound between 4 weeks of and 2 weeks of treatment (P＞0.05). The overall response rate of wound recovery in the experimental group was higher than that in the control group after 4 weeks of treatment, and the difference was statistically significant between the two groups (P＜0.05). Conclusion The Huafu Shengji Paste combined with micro-aerobic therapy in the treatment of stage Ⅳpressure ulcers has a good effect, favorable recovery, and mild side effects, and can significantly improve quality of life of patients, and it is worthy of clinical promotion.

Key words： Stage Ⅳpressure ulcer Huafu Shengji Paste Micro-aerobic therapy Nursing

收稿日期: 2020-09-09

基金资助:江苏省泰州市科技支撑计划社会发展（指导性）项目（20191430）

引用本文:

陈德监；耿小英；周灵芳；陶嫒嫒；杨巧萍；余德华；陈红桂. 化腐生肌膏联合微氧治疗Ⅳ期压疮的临床效果[J]. 中国当代医药, 2021, 28(19): 53-57.
CHEN De-jian GENG Xiao-ying ZHOU Ling-fang TAO Ai-ai YANG Qiao-ping YU De-hua CHEN Hong-gui. Clinical effect of Huafu Shengji Paste combined with micro-aerobic therapy in the treatment of stage Ⅳpressure ulcer. 中国当代医药, 2021, 28(19): 53-57.

链接本文:

http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2021/V28/I19/53

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