Abstract：Objective To explore the effect of Diazepam combined with Racemic Anisodamine Hydrochloride in the elimination of cervical edema during the delivery of primipara.Methods A total of 140 primiparas of vaginal trial labor who were admitted to our hospital from January 2017 to January 2020 were selected as the research objects, and were divided into study group (70 cases) and control group (70 cases) according to the random number table method.The study group was given intravenous injection of Diazepam combined with Racemic Anisodamine Hydrochlo, and the control group was given intravenous injection of Diazepam alone.The time from medication to opening of the uterus,total labor stage, postpartum hemorrhage, cesarean section rate, neonatal asphyxia, disappearance rate of cervical edema and adverse reaction rate of the two groups were recorded.Results The time from medication to opening of the uterus in the study group was (188.32±29.83) min, which was shorter than that in the control group of (246.28±30.24)min, the difference was statistically significant (P＜0.05).The total labor stage in the study group was (313.62±31.82)min, which was shorter than that in the control group of (372.28±33.28) min, the difference was statistically significant(P＜0.05).The postpartum hemorrhage of the study group was (182.37±48.39) ml, less than that in the control group of(233.29±50.28)ml,the difference was statistically significant (P＜0.05).The maternal cesarean section rate in the study group was 4.29%, lower than that in the control group (15.71%), the difference was statistically significant (P＜0.05).The disappearance rate of maternal cervical edema in the study group was 97.14%, high than that in the control group of 82.86%, the difference was statistically significant (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Diazepam combined with Racemic Anisodamine Hydrochloride can effectively eliminate cervical edema in the perinatal period of perinatal women, it could shorten the full opening time of the uterus, shorten the labor process, relieve cervical spasm, reduce postpartum hemorrhage, reduce cesarean section rate, and improve maternal and infant outcomes, worthy of clinical application.
谢 婷；李 斐；刘满英；黄为兰；陈银凤. 地西泮联合盐酸消旋山莨菪碱在初产妇产程中消除宫颈水肿的应用效果[J]. 中国当代医药, 2020, 27(22): 114-117.
XIE Ting；LI Fei；LIU Man-ying；HUANG Wei-lan；CHEN Yin-feng. Application effect of Diazepam combined with Racemic Anisodamine Hydrochloride in the elimination of cervical edema during the delivery of primipara. 中国当代医药, 2020, 27(22): 114-117.
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