补肾壮骨方加减治疗强直性脊柱炎的临床效果

摘要
图/表
参考文献(15)
相关文章 (15)

全文: PDF (0 KB) HTML (35 KB)
输出: BibTeX | EndNote (RIS)

摘要

[摘要]目的探讨补肾壮骨方加减治疗强直性脊柱炎的效果。方法选取我院2016年4月22日～2018年4月22日收治的50例强直性脊柱炎患者作为研究对象，按照奇偶数分组模式分为对照组（25例）与观察组（25例）。观察组采用补肾壮骨方加减治疗，对照组采用柳氮磺胺吡啶片治疗。比较两组患者的总有效率；脊柱活动度、胸廓活动度、指地距、枕墙距；晨僵时间、腰背疼痛积分、红细胞沉降率、血清C-反应蛋白；不良反应总发生率。结果两组患者治疗前的脊柱活动度、胸廓活动度、指地距、枕墙距、晨僵时间、腰背疼痛积分、红细胞沉降率、血清C-反应蛋白比较，差异无统计学意义（P＞0.05）。观察组的总有效率（96.00%）高于对照组（72.00%）（P＜0.05）。观察组治疗后的脊柱活动度为（45.85±3.61）°、胸廓活动度为（3.69±1.47）cm，高于对照组的（35.68±2.66）°、（2.86±1.33）cm（P＜0.05），指地距为（6.11±1.19）cm、枕墙距为（0.33±0.15）cm，低于对照组的（8.95±1.43）、（1.54±0.38）cm（P＜0.05），晨僵时间为（30.15±3.19）min，短于对照组的（35.96±3.55）min（P＜0.05），腰背疼痛积分为（0.32±0.18）分、红细胞沉降率为（14.18±1.28）mm/h、血清 C-反应蛋白为（4.12±0.46）mg/L，低于对照组的（1.32±1.55）分、（18.39±2.41）mm/h、（5.11±0.39）mg/L（P＜0.05）。观察组的不良反应总发生率为 28.00%，低于对照组的 4.00%（P＜0.05）。结论补肾壮骨方加减治疗强直性脊柱炎的效果显著。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章

关键词 ：补肾壮骨方加减')" href="#">

补肾壮骨方加减, 强直性脊柱炎, 效果, 评价

Abstract：[Abstract]Objective To explore the clinical effect of addition and subtraction of Bushen Zhuanggu Recipe in the treatment of ankylosing spondylitis(AS).Methods A total of 50 patients with AS admitted to our hospital from April 22,2016 to April 22,2018 were selected as study objects and they were divided into the control group(n=25)and observation group (n=25)according to the odd/even number group model.In the observation group,addition and subtraction of Bushen Zhuanggu Recipe was used,while in the control group,Sulfasalazine Tablets was used.The total effective rate,spinal activity degree,thoracic range of motion,finger-to-ground distance,occipital-wall distance,morning stiffness time,lumbar-back pain score,erythrocyte sedimentation rate,serum C-reactive protein and the total incidence of adverse reactions were compared between the two groups.Results There was no significant difference in spinal activity,thoracic activity,finger-to-ground distance,occipital wall distance,morning stiffness time,lumbar back pain score,erythrocyte sedimentation rate and serum C-reactive protein before treatment between the two groups(P>0.05).The total effective rate of the observation group(96.00%)was higher than that of the control group(72.00%)(P<0.05).After treatment,the spinal activity degree was(45.85±3.61)°,thoracic range of motion was(3.69±1.47)cm in the observation group,which were higher than those of the control group for(35.68±2.66)°,(2.86±1.33)cm(P＜0.05),finger-to-ground distance was(6.11±1.19)cm,occipital wall distance was(0.33±0.15)cm in the observation group,which were lower than those of the control group for(8.95±1.43),(1.54±0.38)cm(P＜0.05),morning stiffness time was(30.15±3.19)min in the observation group,which were shorter than that of the control group for(35.96±3.55)min(P<0.05),lumbar back pain score was(0.32±0.18)points,erythrocyte sedimentation rate was(14.18±1.28)mm/h,serum C-reactive protein was(4.12±0.46)mg/L in the observation group,which was lower than those of the control group for (1.32±1.55)points,(18.39±2.41)mm/h,(5.11±0.39)mg/L (P<0.05).The total incidence of adverse reactions in the observation group was 28.00%,which was lower than that in the control group(4.00%)(P<0.05).Conclusion The effect of addition and subtraction of Bushen Zhuanggu Recipe in the treatment of ankylosing spondylitis is remarkable.

Key words： Addition and subtraction of Bushen Zhuanggu Recipe Ankylosing spondylitis Effect Evaluation

引用本文:

詹潮滚；陈卓华. 补肾壮骨方加减治疗强直性脊柱炎的临床效果[J]. 中国当代医药, 2019, 26(7): 124-127.
ZHAN Chao-gun CHEN Zhuo-hua. Clinical effect of addition and subtraction of Bushen Zhuanggu Recipe in the treatment of ankylosing spondylitis. 中国当代医药, 2019, 26(7): 124-127.

链接本文:

http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2019/V26/I7/124

[1]	张楠，张英泽，陶庆文，等.补肾壮骨方加减治疗强直性脊柱炎疗效观察[J].中国中西医结合杂志，2017，33（12）：1611-1616.
[2]	杨雄健，刘永恒，王伟群，等.补肾壮骨方加减治疗强直性脊柱炎的临床研究[J].陕西中医，2015，15（11）：1480-1482.
[3]	丁艳杰.补肾壮骨方加减治疗强直性脊柱炎96例[J].风湿病与关节炎，2014，22（7）：25-27.
[4]	连乐峰.补肾壮骨方加减治疗强直性脊柱炎的疗效观察[J].内蒙古中医药，2017，28（36）：20.
[5]	芦北极，查振刚，王贵清，等.补肾壮骨方治疗强直性脊柱炎患者 100例疗效分析[J].临床医学工程，2017，17（7）：893-894.
[6]	石红军，蒲祥虎，徐绍德，等.观察补肾壮骨方加减治疗强直性脊柱炎的临床疗效及安全性[J].中医临床研究，2017，9（31）：94-95.
[7]	唐卉，杨开.补肾壮骨方治疗强直性脊柱炎46例临床观察[J].大众科技，2017，19（8）：84-85，98.
[8]	张楠，阎小萍.补肾壮骨方内服联合寒痹外用方治疗强直性脊柱炎 101例临床观察[J].中医杂志，2013，54（16）：1394-1397.
[9]	徐愿，孔维萍，陶庆文，等.补肾强督方对强直性脊柱炎膜内成骨Wnt/β-catenin通路影响的实验研究[J].中国骨质疏松杂志，2016，22（6）：718-723.
[10]	李亚荣.补肾壮骨方加减治疗强直性脊柱炎疗效分析[J].亚太传统医药，2016，12（1）：127-128.
[11]	金鸥阳.补肾壮骨冲剂治疗强直性脊柱炎疗效观察[J].湖北中医杂志，2017，39（7）：52-53.
[12]	高大勇.补肾壮骨方内服联合寒痹外用方治疗强直性脊柱炎的疗效观察[J].中国药物经济学，2017，12（10）：80-82.
[13]	展文国.健脾补肾温阳通督法治疗强直性脊柱炎[J].云南中医中药杂志，2017，34（2）：86-87.
[14]	庞学丰，雷宗尚，廖键侥，等.补肾壮督法联合柳氮磺吡啶及双氯芬酸钠治疗强直性脊柱炎56例[J].风湿病与关节炎，2014，13（7）：22-24.
[15]	蔡余力，张兴彩，胡亚黎，等.补肾通阳法对强直性脊柱炎患者CRP、BGP及CTX-I影响的研究[J].吉林中医药，2017，37（10）：1005-1007.