Abstract：Objective To investigate the clinical features of children with Mycoplasma pneumoniae pneumonia and pulmonary consolidation, in order to provide evidence in the diagnosis and treatment of such diseases.Methods A retrospective analysis of 112 patients with Mycoplasma pneumoniae pneumonia and pulmonary consolidation who were admitted to our hospital from January 2017 to June 2018 was conducted.The age of the child and hospital stay were calculated.The routine examinations such as blood routine and blood biochemistry were analyzed, and the distribution of abnormal indicators of children was summarized.The cellular immunological indicators including T lymphocytes (CD3+),assistance/induction T lymphocytes (CD3+CD4+), cytotoxic T cells (CD8+), and ratio of assistance/induction T lymphocytes to inhibitory/cell T lymphocytes (CD4/CD8) before and after treatment were compared.The pulmonary function indexes including forced vital capacity (FVC), first second forced expiratory volume (FEV1), one second rate (FEV1/FVC), peak expiratory flow rate (PEF), pre-breathing instantaneous flow rate (FEF25), mid-breath flow velocity (FEF50),late-breath transient flow rate (FEF75), and mid-expiratory flow velocity (FEF25-75) were also compared.The complications, treatment methods and prognosis of the children were counted after the end of the treatment.Results The incidence of Mycoplasma pneumoniae pneumonia with pulmonary consolidation was the highest in school-age children.The abnormal indexes of routine examination included serum C-reactive protein (CRP), neutrophil percentage (N%), lactate dehydrogenase (LDL), etc.The values of FVC, FEV1, PEF, FEF25, FEF50, FEF75 and FEF25-75 were all higher than those before treatment, the differences were statistically significant (P<0.05).There was no significant difference in FEV1/FVC value before and after treatment (P>0.05).The CD3+, CD3+CD4+, CD4/CD8 values were higher than before treatment,and CD8+value was lower than before treatment, the differences were statistically significant (P<0.05).Only one patient developed sequelae after treatment.Conclusion Children of all ages may have Mycoplasma pneumoniae pneumonia and lung consolidation changes.Routine examination can be used to assist in disease screening.After regular treatment,pulmonary function and cellular immunological indicators of children patients return to normal.Most patients have favorable prognosis.
叶国静. 支原体肺炎伴肺部实变改变患儿的临床特征分析[J]. 中国当代医药, 2019, 26(14): 153-156.
YE Guo-jing. Analysis of clinical features in children with Mycoplasma pneumoniae pneumonia and pulmonary consolidation. 中国当代医药, 2019, 26(14): 153-156.
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