Abstract：Objective To analyze the effect of blood pressure changes on the survival of hemodialysis patients during uremia treatment. Methods Ninety patients with uremia admitted to our hospital from December 2016 to December 2018 were selected as subjects. According to the blood pressure, they were divided into normal blood pressure group and hypertension group, with 45 cases in each group. The levels of serum calcium, serum phosphorus, parathyroid hormone, cholesterol, serum albumin and hemoglobin, urea clearance index, hemodialysis weight gain, systolic blood pressure, diastolic blood pressure, mean arterial pressure before and after dialysis were compared between the two groups.The mortality between the two groups was also compared. Results There were no significant differences in serum calcium, cholesterol levels and urea clearance index between the two groups (P＞0.05). The levels of serum phosphorus,parathyroid hormone and weight gain during hemodialysis period in the hypertensive group were higher than those in the normal blood pressure group, serum albumin, and hemoglobin levels were lower than those in the normal blood pressure group, and the differences were statistically significant (P＜0.05). The systolic blood pressure, diastolic blood pressure and mean arterial pressure of the patients in the hypertension group were higher than those in the normal blood pressure group before and after dialysis, and the differences were statistically significant (P＜0.05). The mortality of the hypertension group was 20.00% (9/45), which was higher than that of the normal blood pressure group accounting for 4.44% (2/45), and the difference was statistically significant (P＜0.05). Conclusion Care should be taken to control the patients′ weight during hemodialysis, while avoiding excessive blood pressure reduction after dialysis. Only by controlling the patients′ excessive rise and decrease of blood pressure can their mortality be reduced and the survival time extended.
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