Effect of Azithromycine Combined with Gamma Globulin and Rifampicin in the treatment of children with Refractory Mycoplasma pneumoniae pneumonia
LIU Ying-bo1 CHEN Yang-hua2 LAI Zhong-hua1 MEI Hong1 ZHANG De-qiong3 DENG Mu-yi1
1.Department of Pediatric;Shunde District Lecong Hospital in Foshan City of Guangzhou Province,Shunde 528315,China;
2.Department of Pharmacy,Shunde District Lecong Hospital in Foshan City of Guangzhou Province,Shunde 528315,China;
3.Department of Obstetrics and Gynecology,Shunde District Lecong Hospital in Foshan City of Guangzhou Province,Shunde 528315,China
Abstract:ObjectiveTo investigate the effect of Azithromycine Combined with Gamma Globulin and Rifampicin in the treatment of children with Refractory Mycoplasma pneumoniae pneumonia.MethodsFrom March 2012 to March 2016,93 children diagnosed as refractory Mycoplasma pneumoniae pneumonia in our hospital were randomly divided into control group(47 cases)and observation group(46 cases).The control group was treated with azithromycin,while the treatment group was treated with Azithromycin,Gamma globulin and Rifampicin.The curative effect and symptom improvement time were compared between the two groups.ResultsAfter 3 days of treatment,the effective rate of the observation group was significantly better than that of the control group,the difference was statistically significant(P<0.05);The improvement time of symptoms in the observation group was significantly shorter than that in the control group (P<0.05).ConclusionAzithromycine combined with Gamma Globulin and Rifampicin in the treatment of children with refractory Mycoplasma pneumoniae pneumonia has better clinical efficiency,with can effectively reduce the symptoms improved time with a high clinical value.
刘应波;陈阳华;赖忠华;梅 红;张德琼;邓慕仪. 阿奇霉素、丙种球蛋白、利福平联合用药治疗儿童难治性肺炎支原体肺炎的效果观察[J]. 中国当代医药, 2018, 25(4): 144-146.
LIU Ying-bo;CHEN Yang-hua;LAI Zhong-hua;MEI Hong;ZHANG De-qiong;DENG Mu-yi. Effect of Azithromycine Combined with Gamma Globulin and Rifampicin in the treatment of children with Refractory Mycoplasma pneumoniae pneumonia. 中国当代医药, 2018, 25(4): 144-146.
Seo YH,kim JS,Seo Sc,et al.Predictive value of C-reaetwe protein in response to macrolidls in children with macrolideresistant Mycoplasma pneumoniae pneumonia[J].Korean J Pediatr,2014,57(4);745-752.