The influence of ropivacaine on the analgesia of the postoperative analgesia of the knee arthroscopic surgery with partial infiltration of ropivacaine combined with dexmeidine
WANG Li-ping1 REN Li1 ZENG Lu-lu1 LI Dong-qing1 LIANG Gen-qiang1 XUAN Wen-hu2
1.Department of Anesthesiology,People′s Hospital of Zhuhai City in Guangdong Province,Zhuhai 519000,China;2.Department of Orthopedics,People′s Hospital of Zhuhai City in Guangdong Province,Zhuhai 519000,China
Abstract:Objective To investigate the effect of ropivacaine local infiltration combined with dexmetidine preventive analgesia on postoperative analgesia after knee arthroscopy.Methods From October 2016 to October 2017,120 patients undergoing arthroscopic knee surgery treated in our hospital were selected as the subjects,and randomly divided into two groups,60 cases in each group.The control group was treated with ropivacaine local invasive preventive analgesia,the observation group was treated with ropivacaine local infiltration combined with dexmetidine for prophylactic analgesia.The postoperative analgesia effect,analgesic drug consumption,adverse reactions were compared between the two groups.Results The VAS scores of 1,4,8,12,24 h and 48 h in the observation group were significantly lower than those in the control group,the difference was statistically significant(P<0.05).In the observation group,the postoperative analgesic and 24 h analgesic drug consumption was significantly better than the control group,the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of nausea and vomiting,deep sedation,wakening and restlessness in the observation group (P>0.05).Conclusion Ropivacaine local infiltration combined with dexmetidine prophylactic analgesia can significantly improve the postoperative analgesia of knee arthroscopy,reduce the amount of analgesic drugs,prolong the analgesic time,and the adverse reaction is mild.It has positive clinical significance.
王丽萍;任莉;曾路路;李冬青;梁根强;玄文虎. 罗哌卡因局部浸润联合右美托咪定预防性镇痛对膝关节镜手术后镇痛的影响[J]. 中国当代医药, 2018, 25(21): 76-78.
WANG Li-ping;REN Li;ZENG Lu-lu;LI Dong-qing;LIANG Gen-qiang;XUAN Wen-hu. The influence of ropivacaine on the analgesia of the postoperative analgesia of the knee arthroscopic surgery with partial infiltration of ropivacaine combined with dexmeidine. 中国当代医药, 2018, 25(21): 76-78.