胃镜下肾上腺素联合凝血酶治疗消化性溃疡合并出血的临床效果

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摘要目的观察胃镜下肾上腺素联合凝血酶治疗消化性溃疡合并出血的临床效果。方法选取2014年4月～2015年2月于我院就诊的消化性溃疡合并出血患者76例，采用随机数字表法均分为观察组（n=38）与对照组（n=38）。观察组患者给予肾上腺素联合凝血酶治疗，对照组患者仅给予肾上腺素治疗。比较两组患者的治疗效果。结果观察组患者的治疗效果显著优于对照组，再出血率显著低于对照组（P<0.05）；观察组患者的止血时间、输液时间、住院时间显著短于对照组（P<0.05），输血量显著少于对照组，住院费用显著低于对照组（P<0.05）；治疗后24、48、72 h，两组患者的空腹胃液pH值显著高于治疗前（P<0.05）；观察组患者治疗后24、48、72 h的空腹胃液pH值高于对照组（P<0.05）。结论胃镜下肾上腺素联合凝血酶治疗消化性溃疡合并出血的临床效果显著，能有效缩短止血时间，降低再出血率、住院费用较低，具有临床推广应用价值。

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关键词 ：消化性溃疡, 出血, 胃镜, 肾上腺素, 凝血酶

Abstract：

ObjectiveTo observe the clinical effect of Epinephrine combined with Thrombin in the treatment of peptic ulcer complicated with hemorrhage under gastroscop.Methods76 patients with peptic ulcer complicated with hemorrhage treated in our hospital from April 2014 to February 2015 were selected and they were randomly divided into observation group(n=38)and control group(n=38)using the random number table method.The patients in the observation group were treated with Adrenaline combined with Thrombin,and the control group received：only adrenaline treatment.Treatment effect between the two groups was compared.ResultsThe therapeutic effect of the observation group was significantly better than that of the control group,the rate of rebleeding was significantly lower than that of the control group(P<0.05).The time of stopping,infusion and hospitalization were significantly shorter in the observation group than in the control group,and the amount of blood transfusion was significantly less than that of the control group,and the cost of hospitalization was significantly lower than that of the control group(P<0.05).At after 24 h,48 h and 72 h treatment,the pH value of fasting gastric juice in the two groups was significantly higher than that before treatment and the pH value of fasting gastric juice was significantly higher than that in the control group(P<0.05),and the blood transfusion was significantly lower than that of the control group(P<0.05).ConclusionThe clinical effect of Epinephrine combined with Thrombin in the treatment of peptic ulcer complicated with hemorrhage is significant,which can effectively shorten the time of hemostasis,reduce the rate of rebleeding and cost of hospitalization.It has a clinical promotion and application value.

Key words： Peptic ulcer Bleeding Gastroscope Epinephrine Thrombin

基金资助:江西省景德镇市科技计划项目（20151SFZC028）

引用本文:

邹会. 胃镜下肾上腺素联合凝血酶治疗消化性溃疡合并出血的临床效果[J]. 中国当代医药, 2017, 24(21): 21-23.
ZOU Hui. Clinical effect of Epinephrine combined with Thrombin in the treatment of peptic ulcer complicated with hemorrhage under gastroscope. 中国当代医药, 2017, 24(21): 21-23.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2017/V24/I21/21

[1]	郭佳.金属钛夹联合肾上腺素和立止血内镜下局部注药对消化性溃疡出血的疗效观察[J].现代消化及介入诊疗，2016，21（3）：390-393.
[2]	方柳成.探讨胃镜下兰索拉唑与凝血酶联合治疗消化性溃疡出血的临床疗效[J].当代医学，2014，20（18）：6-7.
[3]	贾淑娟，冯晓宏，王治兰，等.内镜下金属钛夹联合注射肾上腺素治疗消化性溃疡出血的疗效分析[J].中国内镜杂志，2015，21（12）：1278-1280.
[4]	陈龙胜，董金山.胃镜下药物注射联合钛夹辅助治疗消化性溃疡出血效果[J].中国乡村医药，2014，21（16）：14-15.
[5]	白春变.内镜下注射1∶10000肾上腺素治疗消化性溃疡并出血患者的疗效及安全性研究[J].中国药物与临床，2016，16（11）：1637-1639.
[6]	陆福山，陈斌，黄静红，等.胃镜下局部喷洒凝血酶雷贝拉唑联合治疗消化性溃疡出血的疗效观察[J].当代医学，2009，15（16）：87-88.
[7]	孙金锋，张智高，高瑞莲.内镜下胃黏膜肾上腺素注射联合金属钛夹治疗溃疡性上消化道出血的临床研究[J].现代消化及介入诊疗，2016，21（1）：120-122.
[8]	Orlandi RR，Kennedy DW.Revision endoscopic frontal sinus surgery[J].Otolaryngol Clin North Am，2011，34（1）：77-90.
[9]	Koreas GB.Combine traditional Chinese and Western medicine clinical results[J].Rev Endocr Metab Disord，2013，10（12）：73.
[10]	Kew J，Rees GL，Close D.Multiplanar reconstructed computed tomography images improves depiction and understanding of the anatomy of the frontal sinus and recess[J].Am J Rhinol，2013，16（2）：19-23.
[11]	Shelbourne KD，Brueckmann RR.Rush-pin fixation of supracondylar and intercondylar fractures of the femur[J].Bone Joint Surg Am，2014，64（2）：161-169.
[12]	StammbergerHR，KenneyDW，AnatomicTerminologyGroup.Paranasal sinuses：anatomic terminology and nomenclature[J].Ann Otol Rhinol Laryngol，1995，167（Suppl）：7-16.
[13]	刘谋荣，王莉.胃镜下注射肾上腺素联合钛夹治疗有活动出血的非静脉曲张性上消化道出血临床疗效观察[J].河北医学，2014，20（10）：1616-1618.
[14]	周家仍，徐莉，罗旋，等.胃镜引导下联合注射肾上腺素与喷洒超微大黄粉治疗非静脉曲张性上消化道出血的疗效分析[J].中国内镜杂志，2015，21（10）：1069-1072.
[15]	钱燎.内镜下大剂量去甲肾上腺素靶控注射联合氩离子凝固术治疗老年非静脉消化道出血的临床观察[J].广西医科大学学报，2016，33（4）：603-606.