Abstract：ObjectiveTo analyze the effect of Tiopronin combined with Lamivudine in the treatment of pulmonary tuberculosis complicated with chronic hepatitis B.Methods87 cases of pulmonary tuberculosis associated with chronic hepatitis B in our hospital from July 2016 to January 2017 were randomly selected according to clinical treatment and different therapy,all patients were divided into experimental group and control group,40 patients in control group were given anti tuberculosis drugs combined with liver 2HTELfx/4HT treatment,47 patients of experimental group was given Tiopronin combined with Lamivudine with conventional treatment scheme in the treatment of patients,the incidence of adverse reactions and the effects were compared between the two groups.ResultsThe clinical treatment effect of the experimental group was better than that of the control group(95.8%vs.82.5%,P＜0.05).The incidence of adverse reactions in the experimental group was significantly lower than that of the control group,the difference was statistically significant (10.5%vs.20.0%,P＜0.05).ConclusionCombination of tiopronin and Lamivudine with 2HTELfx/4HT in the treatment of patients with pulmonary tuberculosis complicated with chronic hepatitis B can effectively reduce the incidence of adverse reactions such as nausea,vomiting,rash and skin pruritus.
冯霞. 硫普罗宁联合拉米夫定治疗肺结核合并慢性乙型肝炎的效果[J]. 中国当代医药, 2017, 24(15): 34-36.
FENG Xia. Effect of Tiopronin combined with Lamivudine in the treatment of pulmonary tuberculosis complicated with chronic hepatitis B. 中国当代医药, 2017, 24(15): 34-36.
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