Abstract：Objective To investigate the clinical effect of Metoprolol combined with Trimetazidine in the treatment of coronary heart disease(CHF)and heart failure.Methods 78 patients with CHF and heart failure who were admitted to our hospital from October 2013 to October 2015 were randomly divided into observation group(n=39)and control group (n=39).The two groups were given conventional therapy,the observation group on this,basis combined with Metoprolol, Trimetazidine treatment,the clinical indicators of the changes between two groups was compared.Results The total effective rate was 94.87%in the observation group and higher than 76.92%in the control group,the difference was significant(P＜0.01).There were significant differences in cardiac function between the two groups(P＜0.01).The incidence of adverse reactions was significantly lower in the observation group than that in the control group(5.13%vs 20.51%,P＜0.05).Conclusion The combination of Metoprolol and Trimetazidine has better clinical effect and can improve the blood pressure and heart function of patients with CHD and heart failure.Ⅰt has clinical application and popularization value.
李本祥. 美托洛尔联合曲美他嗪治疗冠心病心力衰竭的效果分析[J]. 中国当代医药, 2016, 23(30): 128-130.
LI Ben-xiang. Analysis on the effect of Metoprolol combined with Trimetazidine in treatment of coronary heart disease and heart failure. 中国当代医药, 2016, 23(30): 128-130.
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