Abstract:Objective To investigate the therapeutic effect of Metoprolol combined with Wenxin Granule on arrhythmia of coronary heart disease.Methods Clinical data of 67 cases of arrhythmia in coronary heart disease patients in our center from March to December 2015 were retrospectively analyzed,33 cases using tartaric acid Metoprolol in the treatment of patients were chosen as the control group,34 patients using tartaric acid Metoprolol combined with Wenxin Granule in the treatmentwere chosen as in the observation group.The therapeutic effect of two groups of patientswas observed,clinical controlwas analyzed.Results The total effective rate,incidence of adverse reactions,frequency of arrhythmia and duration of the patients in the observation group [88.2%,23.5%,(8.6±2.5)times,(3.1±0.5)h]were significantly better than those in the control group[66.7%,21.2%,(15.1±5.2)times,(6.1±1.6)h],with significant difference(P<0.05).Conclusion The treatment effect of Metoprolol tartrate combined with Wenxin Granule on arrhythmia of coronary heart disease is good,worthy of clinical application.
周琼;何水带;韩艳. 酒石酸美托洛尔联合稳心颗粒对冠心病心律失常的治疗效果观察[J]. 中国当代医药, 2016, 23(27): 113-115.
ZHOU Qiong;HE Shui-dai; HAN Yan. Treatment effect observation of Metoprolol tartrate combined with W enxin Granule on arrhythm ia of coronary heart disease. 中国当代医药, 2016, 23(27): 113-115.
Zhang LJ,Cardiology DO,Hospital H P.Analysis of Metoprolol combined with Wenxin Granule in the treatment of arrhythmia in coronary heart disease of 25 cases[J].World LatestMed Inform,2015,33(16):22-25.
Dandan LI,Zhu Z.Application effect observation of wenxin particle and amiodarone in the treatment of coronary heart arrhythmia[J].Chin ContMed Educ,2016,58(12):32-38.
Ochiuz L,PopaG,Stoleriu I,etal.Microencapsulation ofMetoprolol tartrate into chitosan for improved oral administration and patient compliance[J].Indust Eng Chem Res,2013,52(49):17432-17441.
Wang X,Zhang X,Chen H.ClinicaleffectofWenxin granule combined with Metoprolol on arrhythmia in elderly patients with coronary heartdisease[J].Chin JGeriatr,2013,32(11):1159-1160.