Infection factors and drug resistance analysis of multi-drug resistant Pseudomonas aeruginosa
LI Yong-wei1 LIU Xin-wei2 WANG Chun-xia1 ZHANG Xiao-qian1 GUO Xiao-lan2
1.Department of Clinical Laboratory，Henan Province Hospital of Traditional Chinese Medicine，Zhengzhou 450002，China；
2.Henan University of Traditional Chinese Medicine，Zhengzhou 450000，China
Abstract：Objective To explore the infection situation and features of multi-drug resistant Pseudomonas aeruginosa in our hospital and to provided basis for clinical infection control.Methods BioMerieux VITEC2-Compact automatic microbiology analysis system was applied to identify and to conduct the drug sensitive test.The drug resistance and clinical materials of 95 strains of multi-drug resistant Pseudomonas aeruginosa separated from clinical samples from January 2013 to January 2015 were analyzed.Results 78.9%（75/95）of the 95 strains of multi-drug resistant Pseudomonas aeruginosa were separated from sputum samples，followed by secretion of wounds（10.5%，10/95）.Trachea intubation，deep venous cannula，and trauma wound were significant infection factors.Drug sensitivity results showed that the drug resistance of ceftriaxone was over 95.00%，and the resistance rate of ceftazidime was 36.30%.Conclusion Infection of multidrug resistant Pseudomonas aeruginosa is related to various invasive catheters and instrumental examinations.Therefore，in the treatment of trauma，effective infection control measures should be formulated to conduct continuous drug resistance monitoring and isolation of those infected with Pseudomonas aeruginosa and to control the spread and prevalence of multi-drug resistant Pseudomonas aeruginosa.
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