Abstract：Objective To exp1ore the pregastroscopy mucosa1 surface anesthetic effects and dispe1 bubb1e action during gastroscopy of dyc1onine hydroch1oride muci1age.Methods 500 patients with gastroscopy from October 2013 to October 2014 of our department were se1ected.The patients were random1y divided into experimenta1 group and contro1 group. Patients in experimenta1 group were sub1ingua1 administration dyc1onine hydroch1oride muci1age 10 m1 before gastroscopy，and patients in contro1 group were sub1ingua1 administration 1idocaine mortar 10 m1 before gastroscopy.Insert mirror one-time success rate，visua1 fie1d definition，the average time of the mirror to the descending part of the duodenum，vio1ent vomiting，extubation，tear of gastric cardia mucosa and number of postoperative pain in two groups were compared.The adverse effects and toxic and side effects in two groups were compared.Results Compared with the contro1 group，the anesthesia effect rating of the experimenta1 group was better with statistica1 difference（P＜0.05）.The effect of the experimenta1 group was better than the contro1 group，with statistica1 difference（P＜0.05）.There were no adverse reactions and side effects in the experimenta1 group and the contro1 group.Conclusion Compared with 1idocaine mortar，dyc1onine hydroch1oride muci1age has obvious mucosa1 surface anesthetic effects，and had no obvious adverse effects and toxic and side effects.The app1ication of dyc1onine hydroch1oride muci1age in pregastroscopy preparation is worthy to be popu1arized.
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