长链非编码RNA与人脑胶质瘤关联性的研究进展

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摘要长链非编码RNA（LncRNA）是一种必需表观遗传调节因子，在脑组织肿瘤的产生和恶性进展过程中具有关键作用，特别是参与了脑胶质瘤的发生与发展。为了解LncRNA在脑胶质瘤中的潜在功能，该文章重点讨论几种特殊的LncRNA的作用机制和临床意义，进一步探讨LncRNA在人脑胶质瘤中的诊断与治疗前景。

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	王行健
	朱淑霞

关键词 ：脑胶质瘤, LncRNA HOTAIR, LncRNA H19, LncRNA CRNDE, LncRNA CASC2, LncRNA XIST

Abstract：Long-chain non-coding RNA(LncRNA)is an essential epigenetic regulator that plays a key role in tumoxrigenesis and malignant progression of brain tissue,especially involved in the development and progression of glioma.In order to understand the potential function of LncRNA in gliomas,this article focuses on the mechanism and clinical significance of several specific LncRNAs and further explores the potential of LncRNA in the diagnosis and treatment of human gliomas.

Key words： Glioma LncRNA HOTAIR LncRNA H19 LncRNA CRNDE LncRNA CASC2 LncRNA XIST

引用本文:

王行健 ;朱淑霞. 长链非编码RNA与人脑胶质瘤关联性的研究进展[J]. 中国当代医药, 2018, 25(6): 21-24.
WANG Xing-jian; ZHU Shu-xia. Correlation between LncRNA with glioma. 中国当代医药, 2018, 25(6): 21-24.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2018/V25/I6/21

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