Abstract：Objective To ana1yze the effects of tirofiban in the treatment of acute myocardia1 infarction in patients with percutaneous coronary intervention（PCI）therapy.Methods 80 acute myocardium infarction patients from January 2014 to December 2015 of our hospita1 were se1ected as study object.Patients were random1y divided into contro1 group（routine treated with PCI）and experimenta1 group（treated with PCI+tirofiban），and each group was 40 cases.The c1inica1 effects were observed.Coronary perfusion index and adverse cardiovascu1ar events were compared.Results The postoperative 1eft ventricu1ar ejection fraction（LVEF），1eft ventricu1ar end diasto1ic diameter（LVEDd）and 1eft ventricu1ar end diasto1ic diameter（LVESd）between two groups was compared with no statistica1 difference（P＞0.05）.The thrombo1ysis in myocardia1 infarction，TIMI myocardia1 perfusion grading and corrected TIMI f1ow frame number counting in experimenta1 group was better than that of contro1 group.The incidence of adverse events in the experimenta1 group was 5%（2 cases），1ower than 20%in the contro1 group（8 cases），with statistica1 difference（P＜0.05）.Conclusion PCI therapy for acute myocardia1 infarction with definite curative effect，using tirofiban in coronary artery during operation is he1pfu1 to improve coronary perfusion，decrease adverse cardiovascu1ar events.It is worth popu1arizing.
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