Abstract：Objective To study the clinical effect of periodental non-surgical treatment in patients with aggressive periodontitis.Methods 68 patients with aggressive periodontitis treated by periodetal non-suryery from August 2013 to August 2015 in our hospital were selected.The periodental index，gomphiasis as well as the level of TNF-α and IL-4 in serum and gingival crevicular fluid were observed.Results After treatment for 1 month，the level of probing depth（PD），bleeding index（BI），attachment loss（AL）was greatly reduced（P＜0.05）；After treatment for 3 months，the level of PD，BI，AL was significantly lower than before treatment（P＜0.05）；After treatment for 3 months，the rate of no gomphiasis was significantly better than before treatment（P＜0.05）.The level of serum tumor necrosis factor-α （TNF-α）and interleukin-4 （IL-4）before treatment and after treatment for 3 months was not signifcant difference （P＞0.05）；The level of TNF-α and IL-4 of gingival crevicular fluid before treatment and after treatment for 3 months was signifcant difference （P＜0.05）.Conclusion The periodental non-surgical treatment has an obvious effect on patients with aggressive periodontitis，and can greatly improve the periodental condition and gomphiasis.
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