Abstract：ObjectiveTo explore contrast cervical cold knife cuts（CKC） and the cervical cone annular cutting （LEEP）treatment of cervical intraepithelial neoplasia（CIN）Ⅲ level effect.Methods82 CINⅢ patients who treated in our hospital from April 2014 to July 2015 were selected for this study.They were divided into two groups according to the random number table method,41 cases in each group.One group patients were treated with CKC,referred to as CKC group.The other were treated with LEEP,referred to as LEEP group.The clinical data of the two groups were observed and recorded.ResultsThe operation time,intraoperative blood loss and postoperative cervical healing time of the two groups of patients was compared,LEEP group were lower than the CKC group,the difference between the two groups was statistically significant(P＜0.05).The recurrence of the two groups of patients at 3,6,12 and 22 months after surgery was compared,CKC group was lower than LEEP group，the difference between the two was statistically significant(P＜0.05).HPV infection between the two groups of patients was compared,patients in the CKC group were significantly lower than those in the LEEP group,the difference was statistically significant(P＜0.05).ConclusionTraditional CKC and LEEP surgery have their own characteristics.The advantages of LEEP is quick and easy operation.Its trauma is small and patients′recovery time is short.But there is also disadvantage,like small range of cutting and cutting edge relapsing easily.Therefore for the treatment of patients with cervical intraepithelial neoplasia,the decision should be made according to their concrete condition and need.
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