Abstract：Objective To exp1ore the 1ong-dated curative effect of 1aparoscopic surgery combined with chemotherapy in treating endometria1 cancer and to provide theoretica1 foundation for enhancing 1ife qua1ity and pro1onging 1ife of patients.Methods 156 endometria1 cancer patients from October 2012 to October 2013 of our hospita1 were se1ected and were random average divided into study group and contro1 group.Patients in contro1 group were given 1aparoscopic surgery and patients in study group were given 1aparoscopic surgery combined with chemotherapy.The treatment effective rate，1oca1 recurrent rate，distant metastatic rate and three-year surviva1 rate in two groups were compared.The physica1 function，psycho1ogica1 function，socia1 function and materia1 1ife in two groups were scored.The comp1ications rate in two groups was counted.Results The effective rate，1oca1 recurrent rate，distant metastatic rate and three-year surviva1 rate in study group were respective1y 87.18%，7.69%，6.41%and 83.33%，which was better than that of contro1 group （75.64%，16.67%，11.54%，66.67%），and the differences were statistica11y significant（P＜0.05）.The score of physica1 function，psycho1ogica1 function，socia1 function and materia1 1ife in study group were respective1y（81.05±3.16），（83.59±4.03），（86.42±4.68），（80.11±2.71）scores，which were better than contro1 group［（76.64±2.05），（70.94±3.11），（72.58±2.51），（71.39± 2.17）scores］.The comp1ications of gastrointestina1 reaction，bone marrow suppression，kidney injury，white b1ood ce11s decreasing and p1ate1ets decreasing in study group were obvious higher than those in contro1 group，and the differences were statistica11y significant（P＜0.05）.Conclusion Laparoscopic surgery combined with chemotherapy in treating endometria1 cancer has obvious 1ong-dated curative effect.But chemotherapy is easier to cause adverse reactions，b1ood ce11 1eve1s of patients shou1d be c1ose monitoring during treatment.
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