Abstract：Objective To investigate the epidemiological characteristics of hand-foot-mouth disease in Ningde area, Fujian province from 2012 to 2015.Methods The information system of China CDC was applied.The epidemiological data were used to statistically analyze the monitoring data and pathogenicity results of hand-foot-mouth disease in Ningde area,Fujian province from 2012 to 2015.Real-time fluorescence quantitative polymerase chain reaction was used to test EV71 virus,coxsackievirus A16,and other enteroviruses.Results The incidence of hand-foot-mouth disease in Ningde area of Fujian Province was analyzed.From 2012 to 2015,the number of incidence was in a reducing trend. The number of severe cases and the number of deaths were significantly reduced in 2013.Severe disease rates,mortality rate,and mortality rate of severe diseases were fluctuating.The laboratory diagnosis composition ratio of severe patients was higher than that in the normal patient(P<0.05).The laboratory diagnosis composition ratio of deceased patients was higher than that in the normal patients and severe patients(P<0.05).The composition ratio of EV71 virus in severe patients and deceased patients was higher than that of coxsackievirus A16 and other enteroviruses (P<0.05).The number of patients in rural area was higher,and the incidence rate of severe diseases,mortality rate and mortality of severe diseases were higher in rural areas than in urban areas(P<0.05).Conclusion The number of hand-foot-mouth disease in Ningde area of Fujian province is in a decreasing trend from 2012 to 2015,and incidence rate of severe diseases and mortality rate,although fluctuating,still remain in a low level.
林厚雄;王德志. 2012～2015年福建宁德地区手足口病流行病学分析[J]. 中国当代医药, 2017, 24(9): 157-159.
LIN Hou-xiong;WANG De-zhi. Epidemiological analysis of hand-foot-mouth disease in Ningde district in Fujian province from 2012 to 2015. 中国当代医药, 2017, 24(9): 157-159.
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