Abstract:Objective To analyze and evaluate the clinical effect of Glucocorticoid combined with Hydroxychloroquine in the treatment of systemic lupus erythematosus rash. Methods A total of 60 patients with systemic lupus erythematosus rash admitted to Shangrao City People's Hospital from January to December 2020 were selected as the research objects. The patients were all female. According to the order of admission,single and double numbers were divided into control group and study group,each with 30 cases. The control group was treated with a single Glucocorticoid,and the study group used Glucocorticoid combined with Hydroxychloroquine for treatment,the lupus erythematosus activity,inflammatory index erythrocyte sedimentation rate,C3 complement,total effective rate of rehabilitation,and occurrence of adverse reactions between the two groups were compared. Results The lupus erythematosus activity and inflammatory index erythrocyte sedimentation rate of the study group were lower than those of the control group,and the C3 complement level was higher than that of the control group,and the differences were significant (P<0.05). The total effective rate of rehabilitation of the study group was higher than that of the control group,and the difference was significant (P<0.05). The incidence of gastrointestinal reactions,mild white blood cell reduction,dizziness and discomfort in the study group were lower than those in the control group,and the differences were significant (P<0.05). Conclusion The application of Glucocorticoids combined with Hydroxychloroquine in the treatment of systemic lupus erythematosus rash can effectively reduce the lupus erythematosus activity score and inflammatory index erythrocyte sedimentation rate,effectively increase the level of C3 complement,and can significantly improve the total effective rate of clinical treatment and reduce various adverse effects The occurrence of reaction,the clinical effect of this treatment method is significant,and it can be widely used in the clinical treatment of the disease.
胡珊. 糖皮质激素联合羟氯喹治疗系统性红斑狼疮皮疹的临床效果[J]. 中国当代医药, 2022, 29(1): 36-38.
HU Shan. Clinical effect of Glucocorticoid combined with Hydroxychloroquine in the treatment of systemic lupus erythematosus rash. 中国当代医药, 2022, 29(1): 36-38.
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