Influence of superficial cervical plexus block on the quality of resuscitation and inflammatory response in patients undergoing general anesthesia for thyroid surgery
1.Department of Anesthesiology,the Affiliated Hospital of Nanjing University of Chinese Medicine,Jiangsu Province,Nanjing 210029,China; 2.Jiangsu Province Key Laboratory of Anesthesiology,Xuzhou Medical University,Jiangsu Province,Xuzhou 221004,China
Abstract：Objective To investigate the influence of superficial cervical plexus block(SCPB)on the resuscitation quality and inflammatory response of patients undergoing thyroid surgery under general anesthesia.Methods A total of 201 patients requiring thyroid surgery in Affiliated Hospital of Nanjing University of Chinese Medicine from March to November 2020 were retrospectively selected as the study subjects.According to whether bilateral ultrasound-guided SCPB was performed,the patients were divided into SCPB group (82 cases)and non-SCPB group (119 cases).Operation time,intraoperative blood loss,serum interleukin-6(IL-6),tumor necrosis factor-α (TNF-α)and interleukin-1 β(IL-1β)levels,intraoperative dosage of propofol,sufentanil and remifentanil,recovery time of spontaneous breathing of patients in anesthesia recovery room (PACU),time of tracheal tube removal and PACU retention time,visual analogue scale(VAS)score and condition of post operative nausea and vomitting(PONV)at 24 h postoperatively were compared between the two groups.Results There were no significant differences in operative time and intraoperative blood loss between the two groups(P>0.05).The intraoperative dosage of propofol,sufentanil and remifentanil in SCPB group was lower than that in non-SCPB group,the difference was statistically significant(P<0.05).The recovery time of spontaneous breathing and the time of tracheal tube removal were earlier in SCPB group than in non-SCPB group,and the PACU residence time was shorter in SCPB group than in non-SCPB group,the differences were statistically significant(P<0.05).The levels of IL-1β,IL-6 and TNF-α in SCPB group were lower than those in non-SCPB group,the differences were statistically significant(P<0.05).24 h after surgery,VAS score and PONV incidence in SCPB group were lower than those in non-SCPB group,the differences were statistically significant(P<0.05).Conclusions Ultrasound-guided bilateral superficial cervical plexus block could improve the quality of resuscitation in patients undergoing general anesthesia for thyroid surgery.The consumptions of intraoperative anesthetics were reduced,the postoperative pain and PONV during the firsr postoperative 24 h were reduced,and postoperative inflammatory reactions were reduced.
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