血必净注射液联合生长抑素治疗重症胰腺炎的临床观察

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Abstract ObjectiveTo investigate the clinical efficacy of Xuebijing Injection combined with somatostatin in the treatment of severe acute pancreatitis.Methods48 patients with severe acute pancreatitis who were admitted to our hospital from February 2013 to April 2016 were randomly divided into control group (n=24)and observation group (n=24)according to the randomization method.The control group was given"basic treatment+somatostatin",and the observation group was given"basic treatment+somatostatin+Xuebijing Injection".The differences in the recovery of gastrointestinal motility,serum related indices,length of ICU stay,complication rate and mortality were observed and compared between the two groups after treatment.ResultsThe recovery of gastrointestinal motility (defecation recovery time,abdomen disappearance time,abdominal pain disappearance time,recovery time of bowel sounds and recovery time of passage of gas),serum related indices(serum amylase,calcium ion,CRP),improvement rate of pancreatic edema,length of ICU stay in the patients with severe acute pancreatitis in the observation group were better than those the control group.The incidence rate of complications and the 28 d mortality rate in the patients with severe acute pancreatitis had no significant difference between the two groups (P>0.05).ConclusionIn the patients with severe pancreatitis,Xuebijing Injection combined with somatostatin can not reduce the incidence rate of complications and mortality rate,but can promote the gastrointestinal motility,reduce the level of inflammation in patients,and reduce length of ICU stay,which is worthy of promotion and application in clinical practice.

Key words： Xuebijing Somatostatin Severe pancreatitis Clinical efficacy

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	CAI Chao-shen

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CAI Chao-shen. Clinical observation of Xuebijing Injection combined with somatostatin in the treatment of severe pancreatitis[J]. 中国当代医药, 2017, 24(11): 41-44.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I11/41

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