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| Evaluation of early diagnostic value of contrast-enhanced ultrasound on small hepatocellular carcinoma at the background of liver cirrhosis |
| YU Hui-lin WANG Jing-bob |
| Department of Ultrasonography,Anshan Cancer Hospital,Liaoning Province,Anshan 114031,China |
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Abstract ObjectiveTo evaluate the early diagnostic value of contrast-enhanced ultrasound on small hepatocellular carcinoma at the background of liver cirrhosis.MethodsIn this study,the observation subjects were all selected from the patients with small liver cancer at the background of liver cirrhosis admitted in our hospital from September 2016 to September 2017.A total of 25 cases(60 lesions)were selected and confirmed by pathological examination after needle biopsy.All subjects were given contrast echocardiography.The sensitivity,the duration of contrast-enhanced ultrasound remission of each lesion,and contrast enhancement mode were recorded.The scores of benign and malignant occupying lesions were analyzed before and after contrast ultrasonography.Results23 patients with small hepatocellular carcinoma at the background of liver cirrhosis were detected by contrast-enhanced ultrasonography.The sensitivity was 92.00%(23/25).The initial enhancement time in the moderate-poorly differentiated cancer group was(14.22±5.35)s，which was significantly shorter than that in the clear cell carcinoma group.The difference between the two groups was statistically significant(P＜0.05);in moderate-poorly differentiated cancer group,the onset time of remission was(60.15±46.57)s.Compared with highly differentiated carcinoma group,the time was significantly shorter,and the difference between groups was statistically significant(P＜0.05);comparison of small hepatocellular carcinoma lesion enhancement mode found that when the ultrasound echo intensity of small liver cancer during parenchyma period was lower than that in the normal liver parenchyma,it was rapid.The detection found that there were 39 lesions in total,accounting for 65.00%.Among them,38 were moderate-poorly differentiated carcinoma lesions and 1 was clear cell carcinoma lesions.Among the 60 lesions,34 cases were diagnosed as malignant,accounting for 56.67%.The ultrasound scores were compared before and after contrast ultrasound.After contrast ultrasound,the score was 5 points for the 51 lesions,and the diagnostic accuracy of small liver cancer was 85.00%.ConclusionFor early diagnosis of small hepatocellular carcinoma at the background of liver cirrhosis,ultrasound contrast has a high clinical value,which can improve the accuracy of ultrasound diagnosis,with high sensitivity.It can be used as an auxiliary imaging method to diagnose small hepatocellular carcinoma at early clinical stage,which is worthy to be further popularized and applied in clinical practice.
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