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Clinical app lication value of liquid thin-layer cytology and biopsy pathology in early stage of cervical cancer and cervical intraepithelial lesions |
YUWen-li |
Maternal and Child Health Care Hospital of Liaoning Province,Shenyang 110005,China |
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Abstract ObjectiveTo explore the clinical application value of liquid thin-layer cytology and biopsy pathology in early stage of cervical cancer and cervical intraepithelial lesions.MethodsWomen with cervical cancer screening from January 2008 to December 2014 in our hospitalwere selected as research subjects,9000 caseswere given liquid based cytology test,891 caseswere diagnosed by biopsy pathology before operation,and the diagnosis results of the twomethodswere observed,finally,based on the final clinical diagnosis results,the diagnostic accuracy of the two methods was analyzed.Results9000 patientswho underwent liquid thin-layer cytology screening ofwomen,according to the principle of cytology and histology diagnosis could differ level,LSIL,HSIL and SCC and final pathological diagnosis coincidence rate was 31.9%(375/1174),83.8%(155/185),100.0%(65/65).91 patients who underwent biopsy pathologic diagnosis of women,CIN 1,CIN 2,CIN 3 stage,SCC and final pathological diagnosis coincidence rate was 42.8%(80/187),61.4% (285/464),71.3%(132/185),100.0%(65/65),with the increase of classification,the diagnostic accuracy was increased,and there was significant difference in the results among each group (P<0.05).ConclusionThe combination of liquid based cytology and biopsy pathology is amethod for the diagnosis of early stage of cervical cancer and cervical intraepithelial lesions,it is beneficial to improve the diagnostic efficiency and can provide a reliable basis for early treatment.
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