Abstract: With the development of information technology, online teaching has gradually been brought into the limelight. The rise of the extensive opening of online courses since 2012 promoted education equity, with more and more online teaching platforms emerging. Due to the widespread of the corona virus disease 2019 (COVID-19), the dates of matriculation had to be postponed. A wide array of categories and levels of schools launched programs of online teaching one after another, in a positive response to "suspending school but not learning", a call by the ministry of education. While online teaching highlights its necessity during this pandemic, it reveals some issues that make the online course fail to meet the expectation of the communication effects, especially for the medical majors. Drawing on the expertise of communication studies, this paper starts with four facets of the issue: disseminator, text, institution, and audience, proposing optimization strategies, including updating the disseminator′s infrastructures of "hardware" and "software", adjusting the content of online teaching, optimizing and upgrading the systems of the platforms of online teaching, and cultivating a disciplined learning habit of the students. This paper eventually seeks to explore the pathways to optimizing the communication effects of online teaching and to enlightening the future online teaching.