Abstract:Objective To investigate the effect of ultrasound-guided saphenous nerve block in the removal of the great saphenous vein. Methods A total of 60 patients with varicose veins of lower extremities who underwent great saphenous vein stripping in People′s Hospital of Pingxiang City from March 2019 to may 2020 were selected and divided into control group and study group according to double-blind method, with 30 cases in each group.The control group received laryngeal mask general anesthesia and the study group received ultrasound-guided cryptonerve block. Hemodynamic indexes mean arterial pressure (MAP) and heart rate (HR) before surgery (T0), 30 min after surgery (T1), 1 h after surgery (T2) and 30 min after surgery (T3) in the two groups were compared. Visual analogue scale (VAS) was used to evaluate the degree of postoperative pain, and the early postoperative time of getting out of bed was compared between the two groups. Results There was no statistically significant difference in MAP and HR between the two groups at T0(P>0.05). The MAP and HR at T1, T2 and T3 in the control group were higher than that of T0, and the differences were statistically significant (P<0.05). There were no statistically significant differences in MAP, HR at T1, T2, T3 and T0 in the study group (P>0.05). The MAP and HR at T1, T2 and T3 in the study group were lower than those in the control group, and the differences were statistically significant (P<0.05). There were no statistically significant differences in VAS score between the two groups at 1 h and 48 h after surgery (P>0.05). VAS scores at 4, 8 and 24 h after surgery in the study group were lower than those in the control group, and the differences were statistically significant (P<0.05).The early postoperative activity time of the study group was shorter than that of the control group, and the difference was statistically significant (P<0.05). Conclusion The application of ultrasonic-guided saphenous nerve block in the great saphenous vein exfoliation can maintain the patients′ intraoperative hemodynamics stable, and the analgesic effect is ideal, which is conducive to the early postoperative recovery of the patient, so it can be regarded as a reliable and effective anesthesia block option, which is worthy of clinical development.