Objective To explore the effect of active circulatory breathing exercise on the course of disease during bronchodilation therapy.Methods From January to May in 2020, a total of 80 patients with bronchiectasis and infection who were admitted to Xinyu Xingang Central Hospital of Jiangxi Province were selected as the research objects.According to different treatment methods, they were divided into the control group and the study group, with 40 cases in each group.The control group received antibiotic treatment, and the study group carried out active circulatory and breathing exercise training on the basis of antibiotic treatment.The hospitalization status, 6-minute walk test results,forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), peak expiratory flow rate, respiratory rate and other pulmonary function indexes of patients were compared between the two groups.Results The duration of antibiotic use and hospital stay in the study group were shorter than those in the control group, and the cost of hospital stay was lower than that in the control group, with statistically significant differences (P＜0.05).There was no significant difference in 6-minute walk test result between the two groups before treatment (P＞0.05); the 6-minute walk test results of two groups after treatment were longer than those before treatment, with statistically significant differences (P＜0.05);the 6-minute walk test result after treatment in the study group was longer than that in the control group, with statistically significant differences (P＜0.05).There were no statistically significant differences between the two groups in lung function indicators such as FVC, FEV1, expiratory peak flow rate, and respiratory frequency before treatment (P＞0.05);after treatment, the FVC and FEV1 of patients of the two groups were higher than those before treatment, the peak expiratory flow rate was faster than that before treatment, and the respiratory frequency was lower than that before treatment, with statistically significant differences (P＜0.05);after treatment, FVC and FEV1 of the the study group were higher than those in the control group, the peak expiratory flow rate was faster than that in the control group, and the respiratory frequency was lower than that in the control group, with statistically significant differences (P ＜0.05).Conclusion Active circulatory respiratory exercise training can effectively shorten the course of patients with bronchiectasis, simultaneously improve lung function, exercise endurance and reduce the cost of hospitalization.