摘要目的 探讨预混胰岛素与胰岛素泵治疗对糖尿病患者的临床效果及血糖达标时间的影响。方法 选取2018年12月～2019年10月辽宁省健康产业集团铁煤总医院内分泌科收治的136 例糖尿病患者作为研究对象，按照给药方式的不同分为参照组与研究组，每组各68 例。参照组采用预混门冬胰岛素30 三针药物治疗方式，研究组采用胰岛素泵输注门冬胰岛素治疗方式。比较两组临床效果及血糖达标时间。结果 两组患者治疗前的空腹血糖与餐后2 h 血糖指标比较，差异无统计学意义（P＞0.05）；治疗半个月后，两组患者的空腹血糖与餐后2 h 血糖指标均低于治疗前，差异有统计学意义（P＜0.05）；研究组患者的空腹血糖与餐后2 h 血糖低于参照组，差异有统计学意义（P＜0.05）；研究组患者的血糖达标时间短于参照组，胰岛素使用量少于参照组，差异有统计学意义（P＜0.05）。研究组患者的胰岛素成本低于参照组，总耗材费用高于参照组，差异有统计学意义（P＜0.05）。结论 胰岛素泵输注门冬胰岛素治疗糖尿病患者，可以在降低胰岛素用量的条件下获得较理想的血糖控制效果，此种方式值得推荐。
Abstract：Objective To investigate the influence of premixed insulin and insulin pump on the clinical effect and the time to reach the blood glucose standard in patients with diabetes.Methods A total of 136 patients with diabetes who were admitted to the Endocrinology Department of Iron and Coal General Hospital of Liaoning Health Industry Group from December 2018 to October 2019 were selected as the research subjects.According to the different methods of administration,divided the patients into control group and study group ,with 68 cases in each group.The control group was treated with Insulin Aspart 30 and the study group was treated with insulin pump Insulin Aspart.The clinical effect and the time to reach the blood glucose standard were compared between the two groups.Results There was no significant difference in fasting blood glucose before treatment and 2 h postprandial blood glucose between the two groups(P＞0.05).Half a month after treatment,fasting blood glucose and 2 h postprandial blood glucose in the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05),and the fasting blood glucose and 2 h postprandial blood glucose in the study group were lower than those in the control group(P＜0.05).The time of reaching the standard of blood glucose was shorter than that in the control group,and the dosage of insulin in the study group was less than that in the control group,the differences were statistically significant(P＜0.05).The cost of insulin in the study group was lower than that in the control group,but the total cost of consumables was higher than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Insulin pump infusion of Insulin Aspart in the treatment of diabetic patients,can reduce the use of insulin under the condition of better blood glucose control effect,this way is worth recommending.
王明. 预混胰岛素与胰岛素泵治疗对糖尿病患者的临床效果及血糖达标时间的影响[J]. 中国当代医药, 2021, 28(2): 71-73.
WANG Ming. Influence of premixed insulin and insulin pump on the clinical effect and the time of reaching the standard of blood glucose in patients with diabetes. 中国当代医药, 2021, 28(2): 71-73.
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