Abstract:Objective To explore the application value of non-invasive positive pressure ventilation(NIPPV)in the emergency treatment of acute respiratory failure.Methods From December 2017 to December 2019,116 patients with acute respiratory failure admitted to Maoming People′s Hospital in Guangdong Province were selected and divided into control group and experimental group according to random number table method,58 cases in each group.Patients in the control group were given conventional symptomatic supportive therapy,and patients in the experimental group were given NIPPV on basic of the control group.The clinical effect,clinical mortality,incidence of ventilator pneumonia,and various indicators of patients before and after treatment were compared between the two groups.Results The total treatment efficiency of the experimental group was 93.10%,which was higher than 74.14% of the control group,and the difference was statistically significant(P<0.05).The mortality and the incidence of ventilator pneumonia in the experimental group were 1.72% and 6.90%,respectively.Compared with 13.79% and 25.86% of the control group,the differences were statistically significant(P<0.05).After treatment,the partial oxygen pressure(PaO2)and blood pH were(79.89±10.98)mmHg and(7.35±0.03)in the experimental group,which were higher than those in the control group of(63.61±7.95)mmHg and(7.26±0.03),and the differences were statistically significant(P<0.05).Carbon dioxide partial pressure(PaCO2),heart rate(HR),and respiratory rate(RR)levels in the experimental group were(44.45±4.19)mmHg,(21.66±6.19)times/min,and(101.34±21.58)times/min,which were lower than those in the control group of(58.47±6.31)mmHg,(26.53±8.69)times/min,and(113.88±21.72)times/min,the differences were statistically significant(P<0.05).Conclusion The application of in the emergency treatment of acute respiratory failure can reduce the incidence of death and complications,effectively improve the patients′ indicators,alleviate the patients′ symptoms,and has significant curative effect.