Abstract：Objective To study the correlation between violent risk and blood lipid levels in vagrant schizophrenia patients in Guangzhou.Methods A total of 180 patients with acute vaginal schizophrenia patients, who were not treated with drugs and conformed to the diagnostic criteria of American Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-V), admitted to the Baiyun Jingkang Hospital and Guangzhou Civil Affairs Bureau Mental Hospital from April to September 2018 were selected as the study group, and another 180 healthy volunteers during the same period were selected as the control group.The levels of serum total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL) and very low density lipoprotein (VLDL) were compared between the two groups.The positive and negative symptom scale (PANSS) and the dynamic appraisal of situational aggression(DASA) were used to analyze the relationship between violent risks and blood lipid levels.Results The levels of TC,HDL and LDL in the study group were lower than those in the control group, and the differences were statistically significant (P<0.05).There were no significant differences in levels of TG and VLDL between the two groups (P>0.05).The levels of TC and LDL were negatively correlated with DASA scores (r=-0.299, -0.262, P<0.05).Conclusion Patients with schizophrenia in the acute phase need to be tested for TC, HDL, and LDL in a timely manner, but treatment options that reduce the above three indicators should be used with caution, which provide three biological reference indicators for violent risk assessment.
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