Abstract：Objective To investigate the clinical effect of aerosol inhalation of Acetylcysteine combined with Beclomethasone Dipropionate in the treatment of capillary bronchitis.Methods A total of 306 patients with capillary bronchitis treated in our hospital from February 2018 to February 2019 were selected as the research subjects.According to the sequence of electronic medical records,they were divided into treatment-A group(n=106),treatment-B group(n=100),and control group (n=100).All children were given routine treatment.In the treatment-A group, aerosol inhalation of Acetylcysteine combined with Beclomethasone Dipropionate was used.In the treatment-B group, aerosol inhalation of Salbutamol combined with Beclomethasone Dipropionate was used.In the control group, aerosol inhalation of Salbutamol alone was applied.The disappearance time of panting, wheezing sound and three concave signs in the three groups was compared.The treatment effect and the occurrence of adverse reactions were observed.Results The disappearance time of panting, wheezing sound and three concave signs in the treatment-A group was shorter than that of the treatment-B group and the control group, the disappearance time of panting, wheezing sound and three concave signs in the treatment-B group was shorter than that in the control group, the differences were statistically significant (P<0.05).The total effectiveness rate in the treatment-A group was higher than that in the treatment-B group and the control group,and the differences were statistically significant (P<0.05).There was no significant difference in the total effective rate between the treatment-B group and the control group (P>0.05).No serious adverse reactions occurred during the treatment of the three groups of children.Conclusion Aerosol inhalation of Acetylcysteine combined with Beclomethasone Dipropionate in the treatment of capillary bronchitis can shorten the disappearance time of clinical symptoms, improve the clinical treatment effect in few adverse reactions and good safety, which is worthy of clinical promotion and application.
史军然； 杜杰静； 高虹； 薛晋玲； 刘连凤. 乙酰半胱氨酸联合丙酸倍氯米松雾化吸入治疗毛细支气管炎的临床效果[J]. 中国当代医药, 2020, 27(12): 90-93.
SHI Jun-ran； DU Jie-jing； GAO Hong； XUE Jin-ling； LIU Lian-feng. Clinical effect of aerosol inhalation of Acetylcysteine combined with Beclomethasone Dipropionate in the treatment of capillary bronchitis. 中国当代医药, 2020, 27(12): 90-93.
Kose M，Ozturk MA，Poyrazoglu H，et al.The efficacy of Nebulized Salbutamol，Magnesium Sulfate，and Salbutamol Magnesium Sulfate combination in moderate bronchiolitis[J].Eur J Pediatr，2014，173（9）：1157-1160.
[14]
Carsin A，Sauvaget E，Bresson V，et al.Early halt of a randomized controlled study with 3% Hypertonic Saline in acute bronchiolitis[J].Respiration，2017，94（3）：251-257.
京公网安备 11010502046607号