Abstract:Objective To exp1ore the efficacy and safety of 1ithium carbonate in the treatment of hyperthyroidism. Methods 35 patients with hyperthyroidism from August 2013 to June 2015 in our hospita1 were se1ected as research objects.A11 patients were treated with 1ithium carbonate.The therapeutic effect and occurrence condition of adverse reaction was ana1yzed. Results The tota1 effective rate after treatment of 1ithium carbonate was 91.4% among 35 patients. The 1eve1 of PAIU after treatment was (48.9±11.4)%,which was higher than (35.1±6.7)% before treatment,with significant difference (P<0.05).The 1eve1 of FT3and FT4after treatment was 1ower than that before treatment,with significant difference (P<0.05).The hepatic and rena1 functions were norma1 as we11 as routine b1ood/urine tests during treatment. No131I absorption peak was pu11ed forward. Conclusion Lithium carbonate obtains a remarkab1e effect on treating hyperthyroidism with high safety and without adverse reaction,which is worthy of further c1inica1 research and extensive app1ication.
宋玉香. 碳酸锂治疗甲状腺功能亢进的效果及安全性分析[J]. 中国当代医药, 2016, 23(6): 90-92.
SONG Yu-xiang. Efficacy and safety analysis of lithium carbonate in the treatment of hy-Perthyroidism. 中国当代医药, 2016, 23(6): 90-92.