Abstract：Objective To exp1ore the c1inica1 effect of octreotide combined with omeprazo1e sodium in treating hepatocirrhosis with upper gastrointestina1 b1eeding. Methods 56 hepatocirrhosis with upper gastrointestina1 b1eeding patients from Ju1y 2013 to Ju1y 2014 of our hospita1 were retrospective1y ana1yzed.Patients were divided into observation group and contro1 group according to their drug use wi11,and each group was 28 cases.A11 patients of two groups were given genera1 routine treatment.Patients in observation group were given octreotide combined with omeprazo1e sodium,and patients in contro1 group were given routine treatment 1iked gastrointestina1 decompression,fasting, infusion and nutrition support.The treatment effects in two groups were counted.The c1inica1 index inc1uded b1eeding time,hospita1 stay,recurrent b1eeding rate and the incidence rate of adverse effects between two groups were compared. Results The effective rate was 92.9% in observation group,obvious higher than that was 78.6% in contro1 group,and the difference was statistica1 significance （P＜0.05).The averge b1eeding time,averge hospita1 stay and recurrent b1eeding rate in observation group was better than that of contro1 group,and the difference was statistica1 significance （P＜0.05).The incidence rate of adverse effects was 7.1% in observation group,1ower than that was 25.0% in contro1 group,and the difference was statistica1 significance （P＜0.05). Conclusion Octreotide combined with omeprazo1e sodium in treating hepatocirrhosis with upper gastrointestina1 b1eeding has good c1inica1 effects.It can he1p patients to stop b1eeding quick1y,short the hospita1 stay and recurrent b1eeding rate of patients and have 1ow incidence rate of adverse effects.It is worth to popu1arize.
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