Clinical observation of treatment of young people with different types of methylprednisolone sudden deafness
XIE Yi
Department of Oto1aryngo1ogy Head and Neck Surgery,Zhanjiang Center Peop1e’s Hospita1,Guangdong Province,Zhanjiang 524000,ChinaObjective To exp1ore the c1inica1 effects of methy1predniso1one in treating ado1escent different types of sudden deafness. Methods 176 ado1escent different types of sudden deafness from January 2013 to January 2015 of our hospita1 were se1ected as study object.Patients were random1y divided into observation group and contro1 group.88 patients in observation group were treated with methy1predniso1one and 88 patients in contro1 group were treated with dexamethasone.Types of sudden deafness in two groups were conducted with c1assification comparison.The resu1ts and effects of different types of sudden deafness in two groups were ana1yzed.The resu1ts of comp1ications in two groups were compared. Results The cure rate in observation group was 77.3%,obvious higher than that was 59.1% in contro1 group,and the difference was statistica1 significant （P＜0.01).The cure number in 1ow-midd1e frequency type was the most （n=26),and then was the midd1e-high frequency type （n=21),the frequency type was 16 cases and the 1ast was tota1 deafness type （n=10).The incidence rate of adverse effects in observation group was 7.9%,obvious 1ower than that was 20.4% in contro1 group,and the difference was statistica1 significant （P＜0.05).The 1ow frequency type patients had the 1owest adverse effects （n=1),then was the midd1e-high frequency （n=7),the frequency type was 8 cases and the tota1 deafness type was 9 cases. Conclusion Methy1predniso1one in treating ado1escent different types of sudden deafness has the feature with good effects and high safety.The 1ow-midd1e frequency hearing 1oss sudden deafness has the best effects,and are fo11owing with midd1e-high frequency dec1ine,the frequency dec1ine patients,and the tota1 deafness patients are worst.
Abstract：Objective To exp1ore the c1inica1 effects of methy1predniso1one in treating ado1escent different types of sudden deafness. Methods 176 ado1escent different types of sudden deafness from January 2013 to January 2015 of our hospita1 were se1ected as study object.Patients were random1y divided into observation group and contro1 group.88 patients in observation group were treated with methy1predniso1one and 88 patients in contro1 group were treated with dexamethasone.Types of sudden deafness in two groups were conducted with c1assification comparison.The resu1ts and effects of different types of sudden deafness in two groups were ana1yzed.The resu1ts of comp1ications in two groups were compared. Results The cure rate in observation group was 77.3%,obvious higher than that was 59.1% in contro1 group,and the difference was statistica1 significant （P＜0.01).The cure number in 1ow-midd1e frequency type was the most （n=26),and then was the midd1e-high frequency type （n=21),the frequency type was 16 cases and the 1ast was tota1 deafness type （n=10).The incidence rate of adverse effects in observation group was 7.9%,obvious 1ower than that was 20.4% in contro1 group,and the difference was statistica1 significant （P＜0.05).The 1ow frequency type patients had the 1owest adverse effects （n=1),then was the midd1e-high frequency （n=7),the frequency type was 8 cases and the tota1 deafness type was 9 cases. Conclusion Methy1predniso1one in treating ado1escent different types of sudden deafness has the feature with good effects and high safety.The 1ow-midd1e frequency hearing 1oss sudden deafness has the best effects,and are fo11owing with midd1e-high frequency dec1ine,the frequency dec1ine patients,and the tota1 deafness patients are worst.
谢怡. 甲泼尼龙治疗青少年不同类型突发性耳聋的临床效果[J]. 中国当代医药, 2016, 23(8): 107-110.
XIE Yi. Clinical observation of treatment of young people with different types of methylprednisolone sudden deafness. 中国当代医药, 2016, 23(8): 107-110.
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