Abstract：Objective To explore the antimicrobial agents use situation of one hospital from 2014 to 2015 and to provide reference basis for clinical application and management of antimicrobial agents.Methods Drug consumption sum ratio，constituent ratio of all kinds of antimicrobial agents drug consumption sum，antimicrobial agents detail that on the top 10 of DDDs，usage rate of antimicrobial agents，antimicrobial agents use intensity of inpatient，antimicrobial agents prevention usage rate for typeⅠincision and microbial sample inspection rate before using antimicrobial agents from 2014 to 2015 of this hospital were selected and counted.Variation trend of all index between two years was compared by making chart.Results The drug consumption sum ratio of antimicrobial agents in this hospital was maintained about 17%.The drug consumption sum ratio of β-lactamase inhibitors and compound preparations of beta lactam antibiotics compatibility was highest （about 35%）.The top 3 DDDs of all kinds of antimicrobial agents were following as quinolones，cephalosporins and macrolides.The top 3 of single use frequency were following as levofloxacin tablet，amoxacllin capsule and clarithromycin tablet.Compared with 2014，the antimicrobial agents usage rate of outpatient，emergence and inpatient respectively decreased 0.23%，-14.77%and 3.26%.Antimicrobial agents use intensity of inpatient patients decreased 4.15 DDDs/hundreds of people every day.Antimicrobial agents prevention usage rate for typeⅠincision decreased 9.21%.Microbial sample inspection rate of overall，limit use and special level use of antimicrobial agents were respectively increased 21.57%，19.42%and 31.63%.Conclusion The hospital antimicrobial drug use gradually tend to be more reasonable，but some indicators have not yet reach the national requirements and still need to further improve management and training.
沈绍清;郭晓辉;任浩洋;周利军;黄幼君. 某医院2014～2015年抗菌药物使用情况分析[J]. 中国当代医药, 2016, 23(10): 156-160.
SHEN Shao-qing;GUO Xiao-hui;REN Hao-yang;ZHOU Li-jun;HUANG You-jun. Analysis of the antimicrobial agents use situation of one hospital from 2014 to 2015. 中国当代医药, 2016, 23(10): 156-160.
Kwint HM，van der Linden PD，Roukens MMB.Intensification of antibiotic use within acute care hospitals in the Netherlands［J］.J Antimicrob Chemother，2012，67（9）：2283-2288.
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