Abstract：Objective To explore the relationship between type O blood pregnant women serum IgG antibody titer and hemolytic direare of newborn，and to provide value reference information for clinical diagnosis and treatment and study in the future.Methods 1350 type O blood pregnant women and newborns from January 2013 to December 2015 of our hospital were selected.Microcolumn gel Coombs test was used to test the titer of pregnant women serum IgG resisting A （B）antibodies and the statistic analysis was conducted for the test results.Results The results showed that among 1350 pregnant women serum，656 with IgG against A （B）antibody titer from 1∶256 to 1∶1024 and the constituent ratio was 48.59%.With the increased of pregnant women serum IgG against A （B）antibody titer，the incidence rate of newborn hemolytic direare increased （P＜0.05）.The incidence rate of newborn hemolytic direare in parents combination of OAB blood type higher was than that of O-A or O-B combination （P＜0.05）.Conclusion Testing type O blood pregnant women serum IgG antibody titer can provide reference basis for the prediction and early diagnosis of newborn hemolytic direare.It has obvious clinical value.
支红霞;周优树;邹标. O型血孕妇血清IgG抗体效价与新生儿溶血病的相关性研究[J]. 中国当代医药, 2016, 23(15): 127-129.
ZHI Hong-xia;ZHOU You-shu;ZOU Biao. Clinical study of the relationshiP between tyPe O blood Pregnant women serum IgG antibody titer and hemolytic direare of newborn. 中国当代医药, 2016, 23(15): 127-129.
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