Clinical efficacy observation of atorvastatin combined with Danhong injection in the treatment of cerebral ischemia caused by vertebral-basilar atherosclerosis
NA Li-sha1 LIZhao-sheng2 YU Long-mei3 ZHAO Yu-mei1 ZHENG Shuai1▲
1.DepartmentofPharmacy,HongqiHospitalofMudanjiangMedicalCollege in Heilongjiang Province,Mudanjiang 157011,China;
2.No.2 Department of Neurology,Hongqi Hospital of Mudanjiang Medical College in Heilongjiang Province,Mudanjiang 157011,China;
3.Department of Laboratory,Hongqi Hospital of Mudanjiang Medical College in Heilongjiang Province,Mudanjiang 157011,China
Abstract:Objective To analyze the clinical effects of atorvastatin combined with Danhong injection in the treatment of cerebral ischemia caused by vertebral-basilar atherosclerosis.Methods Altogether 70 cases of patientswith cerebral ischemia caused by vertebral-basilar atherosclerosis who were treated in our hospital from June 2015 to January 2016 were selected as study object and divided into conventional group and experimental group in accordance with the computer randomly groupingmethod,with 35 cases in each group,patients in conventional group received conventional therapy,while patients in experimental group were administered with atorvastatin and Danhong injection based on the conventional therapy.The clinical efficacy,adverse reaction occurrence rate,as well as the peak blood flow velocity of left vertebral artery,right vertebral artery and basilar artery between two groups were analyzed and compared.Results The total efficiency of conventional group was 77.14%,significantly lower than 94.28%of experimental group with a statistical difference (P<0.05).And the peak blood flow velocity of left vertebral artery,right vertebral artery and basilar artery between two groups showed significant difference(P<0.01).Occurrence rate of adverse reaction between two groups was no significant difference(P>0.05).Conclusion Atorvastatin combined with Danhong injection shows remarkable clinical efficacy in the treatment of cerebral ischemia caused by vertebral-basilar atherosclerosis,which can effectively relieve the patient′s headache,dizziness,blurred vision and other clinical symptoms.
那丽莎;栗昭生;于龙魅;赵玉梅;郑帅. 阿托伐他汀联合丹红注射液治疗椎-基底动脉硬化致脑供血不足的效果观察[J]. 中国当代医药, 2016, 23(24): 28-30.
NA Li-sha;LIZhao-sheng;YU Long-mei;ZHAO Yu-mei;ZHENG Shuai. Clinical efficacy observation of atorvastatin combined with Danhong injection in the treatment of cerebral ischemia caused by vertebral-basilar atherosclerosis. 中国当代医药, 2016, 23(24): 28-30.