补肾活血中药协定方在肾虚证不孕患者中的临床应用研究

摘要
图/表
参考文献(16)
相关文章 (15)

全文: PDF (0 KB) HTML (35 KB)
输出: BibTeX | EndNote (RIS)

摘要目的探讨补肾活血中药协定方在肾虚证不孕患者治疗中的临床效果。方法选取我科2013年2～10月的101例肾虚证型不孕患者（符合供精人工授精适应证）作为研究对象，随机分为对照组（54例）和中药组（47例）。对照组在自然状态下监测卵泡发育，中药组服用补肾活血中药协定方，比较两组的治疗效果。结果中药组的内膜厚度厚于对照组，E2、P水平高于对照组，卵泡数多于对照组，差异有统计学意义（P＜0.05）。中药组的周期妊娠率为29.8%，高于对照组的22.2%，差异有统计学意义（P＜0.05）。结论采用补肾活血中药协定方治疗肾虚型不孕症可明显改善卵巢功能，疗效显著，值得临床推广应用。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	徐璐
	胥杜娟
	胡发明
	梅金凤
	范荷花
	赵玉华

关键词 ：中医药, 补肾活血协定方, 肾虚证, 临床疗效

Abstract：Objective To explore the clinical efficacy of contracting prescription of traditional Chinese medicine for nourishing kidney and activating blood circulation in infertile patients with kidney deficiency syndrome.Methods 101 infertile patients with kidney deficiency syndrome,who were in line with the indication for artificial insemination and received treatment in our department from February to October in 2013 were selected and randomly divided into the control group(54 cases)and the traditional Chinese medicine group(47 cases).The control group was detected follicular development in the natural state,The traditional Chinese medicine group was treated with contracting prescription of traditional Chinese medicine for nourishing kidney and activating blood circulation.The treatment effect of the two groups was compared.Results The intima thickness of the traditional Chinese medicine group was thicker than that of the control group,the levels of E2and P in the traditional Chinese medicine group was higher than that of control group, the number of follicles in the traditional Chinese medicine group was more than that in control group,with significant difference(P＜0.05).The cycle pregnancy rate of the traditional Chinese medicine group was 29.8%,which was higher than 22.2%of the control group,with significant difference(P＜0.05).Conclusion The application of contracting prescription of traditional Chinese medicine for nourishing kidney and activating blood circulation in the treatment of infertility with kidney deficiency syndrome can significantly improve the ovarian function and the clinical efficacy is significant.It is worthy of clinical promotion and application.

Key words： Traditional Chinese medicine Contracting prescription for nourishing kidney and activating blood circulation Kidney deficiency syndrome Clinical efficacy

基金资助:江西省科技计划项目（20122BBG70133）

引用本文:

徐璐；胥杜娟；胡发明；梅金凤；范荷花；赵玉华. 补肾活血中药协定方在肾虚证不孕患者中的临床应用研究[J]. 中国当代医药, 2017, 24(1): 144-146转149.
XU Lu；XU Du-juan；HU Fa-ming；MEI Jin-feng；FAN He-hua；ZHAO Yu-hua. Study on clinical application of traditional Chinese medicine contracting prescription for nourishing kidney and activating blood circulation in infertile patients with kidney deficiency syndrome. 中国当代医药, 2017, 24(1): 144-146转149.

链接本文:

http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2017/V24/I1/144

[1]	贝政平，来佩琍，张斌.妇产科疾病诊断标准[M].北京：科学出版社，2007：298.
[2]	丰有吉，陈晓军.妇产科精要[M].北京：人民卫生出版社，2009：439.
[3]	马宝璋.中医妇科学[M].北京：中国中医药出版社，2004：101-108.
[4]	谢幸，苟文丽，等.妇产科学[M].8版.北京：人民卫生出版社，2014：354.
[5]	国家中医药管理局.中医病证诊断疗效标准[M].南京：南京大学出版社，1994：233-234.
[6]	李春燕，明蕾，张露，等.多次采卵手术对卵巢储备功能的影响[J].武汉大学学报（医学版），2014，35（3）：447-449.
[7]	Veronica J，Roberts SB，Albert ER，et al.Expression of inhibin/activin system messenger ribonucleic acids and proteins in ovarian follicles women with polycystic ovarian syndrome[J].J Clin Endocrinol Metab，1994，79（3）：1434-1438.
[8]	周卫琴，沈宗姬.卵泡生长不良性不孕症INH-ACT-FS系统的改变及其意义[J].江苏医药，2007，33（3）：225.
[9]	Fujiwara T，Lambert-Messerlian G，Sidis Y，et al.Analysis of follicular fluid hormone concentrations and granulosea cell mRNA levels for the inhibin-activin-fiollistatin system：relation to oocyte and embryo characteristics[J].Fertil Steril，2000，74（2）：348-355.
[10]	Fanchin R，Sabino Cunha-Filho J，Schonauer LM，et al.Coordination of early antral follicles by luteal estradiol administration provides a basis for alternative controlled ovarian hyperstimulation regimens[J].Fertil Steril，2003，79（2）：316-322.
[11]	吴日然，廖月婵，叶云，等.测定血清抑制素B水平预测卵巢储备力及调节控制性超排卵用药的研究[J].中华妇产科杂志，2005，40（10）：679-681.
[12]	Seifer DB，Scott RT，Bergh PA，et al.Women with declining ovarian reserve may demonstrate a decrease in day 3 serum inhibin B before arise in day 3 follicle-stimulating hormone[J].Fertil Steril，1999，72（1）：63-65.
[13]	Hohmann FP，Laven JS，de Jong FH，et al.Relationship between inhibin A and B，estradiol and follicle growth dynamics during ovarian stimulation innormo-ovulatory women[J].Eur J Endocrinol，2005，22（16）：395-401.
[14]	夏桂成.中医妇科理论与实践[M].北京：人民卫生出版社，2004：394.
[15]	王玉娥，刘效群，赵瑞刚，等.补肾生血方对不孕症分泌中期子宫内膜ER、PR、VEGF及PDGF影响的研究[J].新中医，2006，38（1）：48-49.
[16]	马灵芝.促排卵汤对高雄激素所致不孕小鼠的实验研究[J].河北中医，2004，26（7）：554-556.