Abstract：ObjectiveTo study the efficacy of thrombolysis combined with anticoagulation in the treatment of severe acute pulmonary thromboembolism.MethodsAltogether 60 patients with severe acute pulmonary thromboembolism who were treated in Department of Emergency in our hospital from January 2015 to January 2017 were selected as the object of this research and randomly divided into the control group and the observation group,with 30 cases in each group.Patients in the control group was only given anticoagulant therapy,the observation group was given thrombolysis and anticoagulant therapy.The clinical efficacy and coagulation function index were compared between the two groups.ResultsThe clinical total effective rate of the observation group was 96.67%,which was higher than 76.67%of the control group,with significant difference (P＜0.05).The levels of PT,FIB and APTT in the observation group after treatment was better than that in the control group,with significant difference (P＜0.05).ConclusionPatients with severe pulmonary thromboembolism may suffer from dyspnea,chest pain,fever and other clinical manifestations.The effect of application of combination of thrombolysis and anticoagulant therapy is better than that of single anticoagulation therapy.
刘彬森. 溶栓联合抗凝治疗急诊重症肺血栓栓塞症的效果观察[J]. 中国当代医药, 2017, 24(23): 40-42.
LIU Bin-sen. Observation of effect of thrombolysis combined with anticoagulation in the treatment of severe acute pulmonary thromboembolism. 中国当代医药, 2017, 24(23): 40-42.
Tanasanvimon S，Garg N，Viswanathan C，et al.High prevalence of recurrent thrombosis in subsets of cancer patients with isolated gonadal vein thrombosis：a single center retrospective study[J].Thromb Res，2014，133（2）：154-157.
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