Red blood cell distribution width and platelet average volume level changes in patients with chronic heart failure and their correlation with plasma N-terminal probrain natriuretic peptide
CHEN Zhao-rong
Department of Internal Medicine,Fanchang District People′s Hospital of Wuhu City,Anhui Province,Wuhu 241200,China
Abstract:Objective To analyze the changes of mean platelet volume(MPV)and red blood cell distribution width(RDW)levels in chronic heart failure,and to explore its relationship with plasma N-terminal pro-brain natriuretic peptide(NT-proBNP).Methods A total of 78 patients with chronic heart failure who were treated in the Department of Internal Medicine of Fanchang District People′s Hospital of Wuhu City from February 2018 to December 2020 were selected as the research objects.According to the New York Heart Association(NYHA)cardiac function classification,the patients were divided into grade Ⅰ/Ⅱ(43 cases)and grade Ⅲ/Ⅳ(35 cases).During the same period,78 healthy subjects were selected as the healthy control group.The MPV,RDW and plasma NT-proBNP detection results of patients after admission were collected,and the MPV,RDW and plasma NT-proBNP levels of the three groups of patients were compared,and their correlation was analyzed.Results RDW,MPV levels and plasma NT-proBNP in chronic heart failure patients were higher than those in healthy control group,and the differences were statistically significant(P<0.05).The levels of RDW,MPV and plasma NT-proBNP in grade Ⅲ/Ⅳwere higher than those in grade Ⅰ/Ⅱ,and the differences were statistically significant(P<0.05).The level of MPV in chronic heart failure patients was positively correlated with plasma NT-proBNP(r=0.223, P=0.048);RDW level was positively correlated with plasma NT-proBNP(r=0.544, P=0.001).Conclusion RDW and MPV have important value in the early diagnosis and evaluation of chronic heart failure.
陈兆荣. 慢性心力衰竭患者红细胞分布宽度、血小板平均体积水平变化及其与血浆N端前脑钠肽相关性分析[J]. 中国当代医药, 2021, 28(25): 84-86转90.
CHEN Zhao-rong. Red blood cell distribution width and platelet average volume level changes in patients with chronic heart failure and their correlation with plasma N-terminal probrain natriuretic peptide. 中国当代医药, 2021, 28(25): 84-86转90.
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