Abstract:Objective To explore the effect of different intervention programs on feeding intolerance in preterm infants.Methods A total of 164 premature infants with feeding intolerance admitted to the Department of Neonatology,People′s Hospital of Yingde City from August 2019 to December 2020 were selected as the research subjects.They were divided into control group and groups A,B and C according to the random lottery method,with 41 cases in each group.The control group was fed with microgastric tube nasogastric feeding,parenteral nutrition and routine feeding and nursing.The A group was treated with non nutritional sucking intervention on the basis of the control group;the B group was treated with three-step prone position intervention on the basis of the control group;the C group was treated with non nutritional sucking and three-step prone position comprehensive intervention on the basis of the control group.The time of daily milk increase,recovery of feeding volume,total intestinal feeding,recovery of birth weight and nasogastric tube indwelling were compared in each group,and the improvement time of feeding intolerance symptoms such as gastric retention,vomiting and abdominal distension were statistically analyzed.Results The daily milk gain of group C was more than that of other groups,while the time for the recovery of the rest of the feeding amount,the time for the whole intestinal feeding,the time for the recovery of birth weight,and the indwelling time of nasogastric tube were shorter than those of other groups,and the differences were statistically significant(P<0.05).The daily milk gain of group A and group B were more than that of the control group,while the recovery time of feeding amount,total intestinal feeding time,recovery time of birth weight and retention time of nasogastric tube were shorter than those of the control group,the differences were statistically signifacant(P<0.05).There was no significant difference in feeding related indexes between group A and group B(P>0.05).The improvement time of feeding intolerance symptoms in group C was shorter than that in other groups,and the difference was statistically significant(P<0.05).The improvement time of feeding intolerance symptoms in group A and group B was shorter than that in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the improvement time of feeding intolerance symptoms between group A and group B(P>0.05).Conclusion Comprehensive intervention such as non nutritive sucking and three-step prone position can improve the symptoms of feeding intolerance and improve the feeding effect of premature infants.