Research progress of EZH2 and its related miRNAs in breast cancer
LUO Yang-yong1,2 WAN Yu2 LIU Jin-ting1 HUANG Jian-jun2▲
1.Graduate School, Guizhou Medical University, Guizhou Province, Guiyang 550004, China;
2.Department of Breast Surgery, Affiliated Hospital of Guizhou Medical University, Guizhou Province, Guiyang 550004, China
Cancer is the most serious disease that endangers human health and life at present, among which breast cancer is a kind of malignant tumor with the increasing rate of morbidity and mortality only second to lung cancer in recent years, and the age of onset tends to be younger.Finding a reliable diagnostic index for breast cancer has become a hot spot in clinical research.Because breast cancer is caused by a small number of self-renewing tumor stem cells,these stem cells may also play a role in tumor recurrence.Thus, genes that regulate cancer stem cells have important implications for cancer control.The Zeste enhancer homologue 2 (EZH2) gene is expressed in increased breast cancer development and plays a role in the increase in the number of breast stem cells.The specific role of EZH2 and the relationship between its miRNA and breast cancer were analyzed
罗扬勇;万 宇;刘晋廷;黄建军. EZH2及其相关miRNA在乳腺癌中的研究进展[J]. 中国当代医药, 2020, 27(20): 19-22.
LUO Yang-yong1,2 WAN Yu2 LIU Jin-ting1 HUANG Jian-jun2▲. Research progress of EZH2 and its related miRNAs in breast cancer. 中国当代医药, 2020, 27(20): 19-22.
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