Abstract:Objective To observe the clinical effect of compound bismuth and magnesium granules-containing quadruple therapy in the treatment of Kirgiz patients with chronic gastritis.Methods 160 cases of Kirgiz patients with chronic gastritis admitted to the People′s Hospital of Kzilsu Kirgiz Autonomous Prefecture from December 2015 to November 2016 were chosen and randomly divided into treatment group and control group,with 80 cases in each group.The patients in the treatment group was given compound Bismuth and Magnesium Granules+Omeprazole+Amoxicillin+Clarithromycin for 14 days;the patients in the control group was given Colloidal Bismuth Pectin+Omeprazole+Amoxicillin+ Clarithromycin for 14 days;and the patients were added the Bismuth preparation for another 14 days in both groups.Hp eradication,gastrointestinal symptoms improvement and adverse drug reaction were compared between 2 groups.Results The rate of Hp eradication in the treatment group was 91.2%,which was slightly higher than that in the control group for 81.2%,and there was no statisticant difference(P>0.05).The upper abdominal pain symptoms improvement rate was 100.0%in the treatment group,which was higher than that in the control group for 92.5%,with statisticant difference(P< 0.05).The ADR rate in the treatment group was 5.0%,lower than that in the control group for 18.8%,with statisticant difference(P<0.01).Conclusion Compound bismuth and magnesium granules-containing quadruple therapy in the clinical treatment on Kirgiz chronic gastritis has a significant effect,it′s remission of upper abdominal pain symptoms has better effects than colloidal bismuth pectin-containing quadruple therapy,what′s more,it decrease the ADR rate.So,it is worthy of clinical promotion between minority areas.
阿依先木·麦麦提. 胃铋镁四联疗法治疗柯尔克孜族慢性胃炎的效果[J]. 中国当代医药, 2017, 24(9): 104-106.
Ayixianmu·Maimaiti. Effect of compound bismuth and magnesium granules-containing quadruple therapy in the treatment of Kirgiz patients with chronic gastritis. 中国当代医药, 2017, 24(9): 104-106.
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