The curative effect of Montelukast in treatment of suffocative bronchitis with respiratory syncytial virus
ZHANG Ying-hui SUN Xiao-li FENG Guo-xian
Department of Pediatrics,the First People′s Hospital of Baiyun District in Guangzhou City(Maternal and Child Care Service Center)in Guangdong Province,Guangzhou 510410,China
Abstract:Objective To observe the therapeutic effects of Montelukast in the treatment of suffocative bronchitis with respiratory syncytial virus(RSV).Methods From October 2014 to October 2016,126 children with suffocative bronchitis with RSV were randomly divided into control(63 cases)and treatment group(63 cases).Infants in control group were treated with conventional therapy,and the experimental group was treated by Montelukast Sodium Chewable Tablets combined with conventional therapy.The efficacy of treatments,pulmonary function tests,recurrence rate,incidence rate of adverse reaction,hospitalization day and total cost were evaluated.Results The total effective rate of experimental group was obviously higher than that of control group(P<0.05).The pulmonary function was obviously improved(P<0.05).The rate of recurrence and incidence rate of adverse reaction in experimental group were significantly lower than control group(P< 0.05).Hospitalization day and total cost of experimental group were reduced compared with control group (P<0.05). Conclusion Montelukast combined withconventional therapy is a high-efficiency and cost-effective therapy in treatment of suffocative bronchitis with RSV.