Protective effect of S-adenosylmethionine on acute liver function lesion after transcatheter arterial chemoembolization in the patients with primary hepatocellular carcinoma
ZENG Xiao-yi
Department of Oncology,the Second People′s Hospital of Pingxiang City,Jiangxi Province,Pingxiang 337000,China
Abstract:ObjectiveTo analyze the protective effect of S-adenosylmethionine on acute liver function lesion after transcatheter arterial chemoembolization(TACE)in the patients with primary hepatocellular carcinoma.Methods80 patients with primary hepatocellular carcinoma who were admitted in our hospital and treated by TACE from January 2015 to January 2017 were selected as the study subjects.According to the comprehensive randomized sequential method,the patients were divided into 40 cases in the control group and 40 cases in the observation group.The control group was given routine hepatoprotective therapy,including TACE treatment,gantaile tablets+Vitamin C+creatinine injection and other drug intervention.The observation group was given S-adenosylmethionine after the treatment on the basis of the control group.The changes of liver function were compared between the two groups at different time points before and after treatment.ResultsAfter treatment,the liver function indices in the two groups were compared and the differences were not statistically significant(P>0.05);the level of liver function indices in the observation group 7 d after the treatment was lower than that in the control group,and the difference was statistically significant(P<0.05);the satisfaction rate with treatment in the observation group was significantly higher than that in the control group,and the results were significantly different(P<0.05).ConclusionS-adenosylmethionine intravenous infusion can be used to alleviate the acute liver function injury and promote the recovery of liver function in patients with hepatocellular carcinoma after TACE.
曾筱怡. S-腺苷蛋氨酸对原发性肝癌介入化疗栓塞后急性肝功能损害的保护作用[J]. 中国当代医药, 2017, 24(32): 130-132.
ZENG Xiao-yi. Protective effect of S-adenosylmethionine on acute liver function lesion after transcatheter arterial chemoembolization in the patients with primary hepatocellular carcinoma. 中国当代医药, 2017, 24(32): 130-132.