Clinical study of different dose of Rosuvastatin for elderly patients with coronary artery borderline lesion
YUAN Shan-bin1 WU Yong-hua2 GAN Guang-ping1
1.Department of Emergency and Critical Care Medicine,Xinfeng County People′s Hospital in Jiangxi Province,Xinfeng 341600,China;
2.Department of Science and Education,Xinfeng County People′s Hospital in Jiangxi Province,Xinfeng 341600,China
Abstract:Objective To explore the clinical effect of different dose of Rosuvastatin for elderly patients with coronary artery borderline lesion.Methods 220 elderly patients with coronary artery borderline lesion treated by our hospital from May 2014 to May 2015 were selected and they were randomly divided into the two groups.The observation group (111 patients)was treated by high-dose of Rosuvastatin,while the control group(109 patients)was treated by small dose of Rosuvastatin.Clinical symptom remission rate,incidence rate of adverse reactions and IMT of carotid and TG,HDL-C, hs-CRP,LDL-C,TC level in patients between two groups was compared respectively.Results IMT value[(1.36±0.05)cm], incidence rate of adverse reactions(0.90%),and TG value[(0.32±0.05)mmol/L],HDL-C value[(1.89±1.85)mmol/L], hs-CRP value[(9.06±1.42)μg/L],LDL-C value[(0.30±0.08)mmol/L]and TC value[(1.78±0.32)mmol/L]after treatment in observation group was obviously better than that of control group[(2.36±0.98)cm,29.36%,(1.54±0.65)mmol/L, (1.02±0.69)mmol/L,(13.47±4.25)μg/L,(1.36±1.47)mmol/L,(1.57±0.04)mmol/L]respectively(P<0.05).Conclusion High dose of Rosuvastatin for elderly patients with coronary artery borderline lesion is more significant.
袁善斌;吴永花;甘光平. 不同剂量瑞舒伐他汀对老年冠状动脉临界病变患者临床研究[J]. 中国当代医药, 2017, 24(1): 59-61.
YUAN Shan-bin;WU Yong-hua;GAN Guang-ping. Clinical study of different dose of Rosuvastatin for elderly patients with coronary artery borderline lesion. 中国当代医药, 2017, 24(1): 59-61.
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