妊娠期甲状腺功能减退症对妊娠期高血压疾病以及母婴结局的影响

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Abstract Objective To explore the relationship between hypothyroidism and hypertensive disorder complicating pregnancy and its influence on maternal and infant outcomes.Methods From October 2018 to February 2020,156 cases of pregnant women in Women and Children′s Hospital of Jinzhou were selected as the research objects,and they were divided into two groups according to whether hypothyroidism occurred during pregnancy.The pregnant women with hypothyroidism were enrolled in the study group,with 85 cases in total;the pregnant women without hypothyroidism were enrolled in the control group,with a total of 71 cases.The levels of triiodothyronine (FT3),thyroid hormone (FT4) and thyroid stimulating hormone (TSH) were detected for the two groups,and the blood pressure during pregnancy was observed.Finally,the pregnancy outcomes and the impact on the fetus of the two groups were compared.Results The levels of FT3 and FT4 in the study group were lower than those in the control group,while the TSH level in the study group was higher than that in the control group,with statistically significant differences (P＜0.05).The incidence of pregnancy induced hypertension in the study group was 5.63%,higher than 20.00% in the control group,with statistically significant difference (P＜0.05).The incidence rates of premature birth,premature rupture of membranes,cesarean section,fetal distress and postpartum hemorrhage in the study group were higher than those in the control group,with statistically significant differences (P＜0.05).The incidence rates of neonatal infection,jaundice,respiratory distress syndrome and asphyxia in the study group were higher than those in the control group,with statistically significant differences (P＜0.05).Conclusion Hypothyroidism in pregnant women will increase the risk of pregnancy induced hypertension,and the probability of premature delivery,premature rupture of membranes and postpartum hemorrhage is higher,and it is also easy to induce neonatal jaundice,asphyxia and respiratory distress syndrome.

Key words： Pregnancy Hypothyroidism Gestational hypertension Maternal and infant outcomes

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	Articles by authors
	LYU Dong-mei
	SHANG Min-jie
	TIAN Xiao-ying
	PAN Zhong-min
	CHEN Shuang

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LYU Dong-mei,SHANG Min-jie,TIAN Xiao-ying, et al. Influence of hypothyroidism on hypertensive disorder complicating pregnancy and maternal and infant outcomes[J]. 中国当代医药, 2021, 28(6): 94-96.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I6/94

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