地佐辛对患儿腹腔镜手术麻醉苏醒期躁动的影响

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Abstract Objective To explore the influence of Dezocine on emergence agitation of surgical anesthesiain in children given laparoscopic surgery.Methods 60 children scheduled for laparoscopic high ligation of hernia sac treated in the First People′s Hospital of Lianyungang from April 2016 to November 2017 were selected and they were randomly divided into the Dezocine group (n=30)and control group (n=30).15 min before the end of operation,Dezocine group was given 0.1 mg/kg Dezocine,while the control group was given the same volume of normal saline.The operation time,extubation time and modified Aldrete score when entered into the post-anesthesia care unit(PACU)and PACU retention time were observed and recorded.Mean arterial pressure(MAP)and heart rate(HR)were recorded at the time before anesthesia(T0),drug withdrawal(T1),extubation(T2)and 5 min after extubation(T3).At the same time,pediatric anesthesia emergence delirium(PAED)score,modified children′s hospital of Eastern Ontario Pain Scale(m-CHEOPS)score and the incidence of adverse reactions were recorded.Results PAED score and m-CHEOPS score in the Dezocine group were lower than those in the control group(P＜0.001).There were no significant difference in the extubation time,the modified Aldrete score or PACU retention time between the two groups(P＞0.05).MAP and HR of the Dezocine group were lower than those of the control group at T1and T2(P＜0.05).The HR of Dezocine group was slower than that of the control group at T2and T3(P＜0.05).Adverse reactions were not found in the two groups.Conclusion Intravenous infusion of 0.1 mg/kg Dezocine before the end of operation in children′s laparoscopic high ligation of hernia sac can prevent the incidence of emergence agitation after general anesthesia but don′t prolong the postoperative recovery and extubation time in children.The hemodynamics was stable and adverse reactions were not observed in children.

Key words： Dezocine Children General anesthesia Laparoscopic surgery Emergence agitation

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	LIU Dong-zhi
	ZHAO Zhi-bin

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LIU Dong-zhi,ZHAO Zhi-bin. Influence of Dezocine on emergence agitation of surgical anesthesiain in children given laparoscopic surgery[J]. 中国当代医药, 2018, 25(14): 17-20.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I14/17

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